Pérez BCF, Espinosa PKE, Quiroz CO, Gallegos GAC, Zárate OA, Torres GG, Hurtado MR

Language: Spanish
References: 19
Page: 171-175
PDF size: 220.19 Kb.

ABSTRACT

Krukenberg’s tumor is a metastasis to ovary from a neoplastic whose origin is from gastrointestinal adenocarcinoma. Dr. Friederich Krukenberg, first described in 1986 a morphology that was characterized by mucus-secreting cells shaped seal ring. Herein we inform a case of hematological malignancy (Non-Hodgkin lymphoma diffuse large B-cell immunophenotype CD20+) that presented a clinical behaviour and pattern of spread similar to Krukenberg’s tumor and after chemotherapy treatment, the patient has seven years on first remission. To our knowledge, this is the first case report of Non-Hodgkin Lymphoma with Krukenberg features.

REFERENCES

1. Tamayo LT, Santana IO, Fiallo CL. Tumor de Krukenberg. Rev Cubana de Obstet Ginecol. 2014; 40 (1): 96-101.

2. Prat J. Ovarian carcinomas, including secondary tumors: diagnostically challenging areas. Mod Pathol. 2005; 18: S99-S111.

3. Crum C, Nucci M, Lee K. Diagnostic gynecologic and obstetric pathology. 2nd ed. Philadelphia, PA: El Servier Saunders, 2011.

4. Fletcher C. Diagnostic histopathology of tumors. 4th ed. Cap 8. 336-337.

5. Padni S, Paul TR, Challa S et al. Primary extra nodal Non Hodgkin Lymphoma: A 5 year retrospective analysis. Asian Pac J Cancer Prev. 2012; 13 (10): 4889-4895.

6. Ding D, Pei W, Chen W et al. Analysis of clinical characteristics, diagnosis, treatment and prognosis of 46 patients with primary gastrointestinal non-Hodgkin lymphoma. Mol Clin Oncol. 2014; 2 (2): 259-264.

7. Baldomir Mesa T, Castillo García R. Tumor de Krukenberg. Presentación de caso. Acta Médica del Centro. 2012; 6 (2).

8. Nedomova R, Papajik T, Prochazka V et al. Cytogenetics and molecular cytogenetics in diffuse large B-cell lymphoma (DLBCL). Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2013; 157 (3): 239-247.

9. Ghielmini M, Montoto S. Lymphomas essentials for clinicians. 2012. ESMO press

10. Tilly H, Dreyling M. Diffuse large B-cell non-Hodgkin’s lymphoma: ESMO Clinical Recommendations for diagnosis, treatment and follow-up. Ann Oncol. 2009; 20 (4): 110-112.

11. Bautista-Quach M, Ake C, Chen M et al. Gastrointestinal lymphomas: Morphology, immunophenotype and molecular features. J Gastrointest Oncol. 2012; 3 (3): 209-225.

12. Williams. Manual de hematología. Capítulo 100, 8a ed. McGraw-Hill.

13. Sarmiento-Chavero M, Gabiño-López N. Entendiendo el inmunofenotipo de las neoplasias de células B maduras. Artículo de revisión. Rev Invest Med Sur Mex. 2012; 19 (4): 212-221.

14. Hu R, Zhang R et al. Ovary involvement of diffuse large B-cell lymphoma. Am J Case Rep. 2012; 13: 96-98.

15. Taskin MI, Gokgozoglu L, Kandemir B. Primary ovary large B-cell lymphoma. Hindawi Publishing Corporation. Case Rep Obstet Gynecol. 2013; 2013: 493836.

16. Senol T, Doger E, Kahramanoglu I et al. Five cases of non-Hodgkin lymphoma of the ovary. Hindawi Publishing Corporation. Case Reports in Obstetrics and Gynecology. 2014.

17. Jung IS, Kim KS et al. A case report of primary ovarian lymphoma presenting as a rectal submucosal tumor. J Korean Soc Coloproctol. 2012; 28 (2): 111-115.

18. Takahashi H, Tomita N, Yokoyama M et al. Prognostic impact of extranodal involvement in diffuse large B-cell lymphoma in the Rituximab era. Cancer. 2012; 4166-4172.

19. Larouche JF, Berger F, Chassagne-Clément C et al. Lymphoma recurrence 5 years or later following diffuse large B-cell lymphoma: Clinical characteristics and outcome. J Clin Oncol. 2010; 28 (12): 2094-2100.