2016, Number 620
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Rev Med Cos Cen 2016; 73 (620)
Carcinoma de sitio primario desconocido
Vargas CDA
Language: Spanish
References: 10
Page: 583-586
PDF size: 179.53 Kb.
ABSTRACT
Carcinomas of unknown
primary have a big impact
on the patient’s survival rate,
this being that it has been
proven that their molecular
genetic bases are different from
those primary cancers where
origin is known, tending to
behave differently and making
treatment unspecific. Clinical
evaluation has improved greatly
due to merit on diagnostic
development and empirical
treatment, thus significantly
increasing the median patient
survival rate.
REFERENCES
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Casciato, D; Territo, M. (2013). Manual de Oncología Clínica (7ma. Edición). Wolters Kluwer Health, Barcelona España, pagina 493- 505.
DeVita V., Lawrence T., & Rosenberg S., (2011). CANCER PRINCIPLES & PRACTICE OF ONCOLOGY (10ma. Ed.) United States of America; Wolters Kluwer Health, pagina 2516 – 2536.
Fizazi, K., Greco, F. A., Pavlidis, N., Pentheroudakis, G., & ESMO Guidelines Working Group. (2011). Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and followup. Annals of oncology,22(suppl 6), vi64-vi68.
Hainsworth, J. D., Rubin, M. S., Spigel, D. R., Boccia, R. V., Raby, S., Quinn, R., & Greco, F. A. (2013). Molecular gene expression profiling to predict the tissue of origin and direct site-specific therapy in patients with carcinoma of unknown primary site: a prospective trial of the Sarah Cannon research institute. Journal of Clinical Oncology, 31(2), 217-223.
Longo,L.,Jamenson, L., Fauci, A., Hause,S.& Loscalzo,J. (2015). HARRISON’S PRINCIPLES OF INTERNAL MEDICINE (19 EDITION). McGraw-Hill Education, United States. Pág. 120e1.
Ross, J. S., Wang, K., Gay, L., Otto, G. A., White, E., Iwanik, K., & Stephens, P. J. (2015). Comprehensive genomic profiling of carcinoma of unknown primary site: new routes to targeted therapies. JAMA Oncology, 1(1), 40-49.
Senra Armas, L. A., & Menéndez Pérez, R. (2014). Identificación de tumor primario en pacientes con metástasis como forma de presentación de cáncer.Revista Cubana de Medicina, 53(4), 402- 416.
Vikeså, J., Møller, A. K., Kaczkowski, B., Borup, R., Winther, O., Henao, R., & Nielsen, F. C. (2015). Cancers of unknown primary origin (CUP) are characterized by chromosomal instability (CIN) compared to metastasis of know origin. BMC cancer, 15(1), 151.
Varadhachary, G. & Raber, M. Cancer of Unknown Primary Site (August 21, 2014). The New England Journal Medicine, 371:757-765.