2015, Number S1
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Med Cutan Iber Lat Am 2015; 43 (S1)
Pyoderma gangrenosum as cutaneous manifestation of Wegener’s granulomatosis
García-Río I, Almeida LV, Julia MM, Martínez SAM, Fraile AMC, Viguri DA
Language: Spanish
References: 17
Page: 51-54
PDF size: 332.56 Kb.
ABSTRACT
Wegener’s granulomatosis is a multisystemic vasculitis in which cutaneous lesions can frequently be found. Multiple types of skin lesions have been described, the most common being palpable purpura, subcutaneous nodules and necrotic papules. Only between 6 and 13% of cases of Wegener’s granulomatosis are first manifested in the skin. We present a case of Wegener’s granulomatosis which began in a limited or incomplete form, with cutaneous lesions of pyoderma gangrenosum and its evolution led to confirm the diagnosis.
REFERENCES
Goodman GC, Churg J. Wegener’s granulomatosis: pathology and review of the literature. Arch Pathol. 1954; 58: 533-553.
Leavitt RY, Fauci AS, Bloch DA, Michel BA, Hunder GG, Arend WP el al. The American College of Rheumatology 1990 criteria for the classification of Wegener’s granulomatosis. Arthritis Rheum. 1990; 33: 1101-1107.
Zycinska K, Wardyn K, Zielonka TM, Nitsch-Osuch A, Smolarczyk R. Cutaneous changes: an initial manifestation of pulmonary Wegener’s granulomatosis. Adv Exp Med Biol. 2013; 755: 307-310.
Fauci AS, Hayes BF, Katz P, Wolff SM. Wegener’s granulomatosis : prospective clinical and therarpeutic experience with 85 patients for 21 years. Ann Intern Med. 1983; 98: 76-85.
Daoud MD, Gibson LE, DeRemee RA, Specks U, El-Azhary RA, Daniel-Su WP. Cutaneous Wegener’s granulomatosis: clinical, histopathologic and immunopathologic features of thirty patients. J Am Acad Dermatol. 1994; 31: 605-612.
Frances C, Du LT, Piette JC, Saada V, Boisnic S, Wechsler B et al. Wegener’s granulomatosis: dermatological manifestations in 75 cases with clinicopathologic correlation. Arch Dermatol. 1994; 130: 861-867.
Micali G, Cook B, Ronan S, Yadgir J, Solomon LA. Cephalic pyoderma gangrenosum (PG)-like lesions as a presenting sign of Wegener’s granulomatosis. Int J Dermatol. 1994; 33: 477-4780.
Handfield-Jones SE, Parker SC, Fenton DA, Newton JA, Greaves MW. Wegener’s granulomatosis presenting as pyoderma gangrenosum. Clin Exp Dermatol. 1992; 17: 197-200.
Marzano AV, Balice Y, Papini M, Testa R, Berti E, Crosti C. Localized Wegener’s granulomatosis. J Eur Acad Dermatol Venereol. 2011; 25: 1466-1470.
Kuchel J, Lee S. Cutaneous Wegener’s granulomatosis: a variant or atypical localized form? Australas J Dermatol. 2003; 44: 129-135.
Comfere NI, Macaron NC, Gibson LE. Cutaneous manifestations of Wegener’s granulomatosis: a clinicopathologic study of 17 patients and correlation to antineutrophil cytoplasmic antibody status. J Cutan Pathol. 2007; 34: 739-747.
Barksdale SK, Hallahan CW, Kerr GS, Fauci AS, Stern JB, Travis WD. Cutaneous pathology in Wegener’s granulomatosis: a clinicopathologic study of 75 biopsies in 46 patients. Am J Surg Pathol. 1995; 19: 161.
Rao JK, Weinberger M, Odoone EZ, Allen NB, Landsman P, Feussner JR. The role of antineutrophil cytoplasmic antibody (c-ANCA) testing in the diagnosis of Wegener granulomatosis: a literature review and meta-analysis. Ann Intern Med. 1995; 123: 925-932.
Sinovich V, Snow J. Protracted superficial Wegener’s granulomatosis. Australas J Dermatol. 2003; 44: 207-214.
Kihiczak D, Nychay SG, Schwartz RA, McDonald RJ, Churg J, Lambert C. Protracted superficial Wegener’s granulomatosis. J Am Acad Dermatol. 1994; 30: 863-866.
Tadema H, Heeringa P, Kallenberg CG. Bacterial infections in Wegener’s granulomatosis: mechanisms potentially involved in autoimmune pathogenesis. Curr Opin Rheumatol. 2011; 23: 366-371.
Lutalo PM, D’Cruz DP. Diagnosis and classification of granulomatosis with polyangiitis (aka Wegener’s granulomatosis). J Autoimmun. 2014; 48-49: 94-98.