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2016, Number 1

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Cuba y Salud 2016; 11 (1)

Infections increase for methicillin resistant Staphylococcus aureus in a children hospital in Cuba

Monzote LA, Toraño PG, Díaz NL, Valdés-Dapena VM

Language: Spanish
References: 30
Page: 9-15
PDF size: 1209.74 Kb.


ABSTRACT

Objectives: To define the Methicillin resistant Staphylococcus aureus isolates investigated and to describe oversensitivity to non beta-Lactams anti infective agents.
Methods: A prospective study was conducted during the period 2010-2012 in “Juan Manuel Márquez” Children Hospital in Havana, which included 333 isolates of Methicillin-resistant Staphylococcus aureus (MRSA), taken from different clinical samples of admitted patients. To confirm MRSA methods Cefoxitin disk diffusion and broth micro dilution Oxacillin were used. Oversensitivity to 14 non beta-Lactams anti infective agents was performed by micro dilution method and disk diffusion (Kirby-Bauer).
Results: A high Methicillin resistance (- 59.3% 52.4%) was demonstrated. It revealed the emergence of skin infectious and soft tissues (62.5%) MRSA. High Erythromycin resistance (82%) and Ciprofloxacin (73.5%) was confirmed. Sensitivity to Cotrimoxazole, Clindamycin and Vancomycin, confirmed them as first-line anti infective agents to the treatment.
Conclusions: It is evidence a tendency to increase in MRSA infections and noted as an emerging clinical and epidemiological problem for the different services of the hospital, which demand the implementation of a system for active surveillance and control.


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