Pérez-Rodríguez I, Pérez-Salgado D, Compeán-Dardón MS, Staines-Orozco MG, Ortiz-Hernández L

Language: Spanish
References: 20
Page: 396-406
PDF size: 478.33 Kb.

ABSTRACT

Objetive: To analyze the relationship of the factors associated with treatment (acute and chronic effects, restrictions by taking medications, and perceived benefits) and non-adherence to antiretroviral treatment (ART).
Material and Method: A transversal, analytic and comparative survey was conducted with 547 people with HIV who were receiving care at two public institutions from Mexico City. A questionnaire was used to measure adherence to ART, acute (eg. diarrhea, fatigue or nausea) and chronic side effects (eg. lipodystrophy and hypercholesterolemia), restrictions by taking medications, and perceived benefits.
Results: Fatigue, weakness, vomiting, diarrhea and nausea were the most common acute side effects; lipodystrophy was the most frequent chronic side effect; taking medicine with empty stomach was the main constraint, and most people perceived benefits of ART. The main factors for non-adherence to ART were chronic side effects and distrust. Patients that reported a chronic effect (OR=2.23, p=0.001) had higher probability of non-adherence to ART in the last month.
Conclusions: Patients with HIV whom reported chronic effects are more likely to non-adherence. These findings might be taken into account by health care workers to promote adherence to ART among people with HIV.

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