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2016, Number 1

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Invest Medicoquir 2016; 8 (1)

A vaccine candidate for solid tumors with vascular endothelial growth factor as target

Hind Selman-Housein BK, Hernández BF, Morera DY, Martín BY, Ayala ÁM, Gavilondo CJV

Language: Spanish
References: 24
Page: 148-155
PDF size: 145.37 Kb.


ABSTRACT

We present a short report that give information about rationality of active and passive immunotherapies in cancer. It is presented a vaccine candidate for solid tumors with vascular endothelial growth factor as target; it main results in pre-clinic studies that allowed clinical trials in humans. Benefits of active immunotherapies over passive are discussed, presenting differences between them, analyzing safety reports of phase I clinical trial of vaccine candidate presented, against the antiangiogenic by excellence approved for humans use (bevacizumab).


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