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ISSN 1561-3186 (Electronic)

2015, Number 2

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Rev Acta Médica 2015; 16 (2)

Results of using ophthalmic emulsion of cyclosporine A 0.05% in dry eye

Alemañy GJ, Aragonés CB, Dotres HF, Alfonso GBL

Language: Spanish
References: 18
Page:
PDF size: 150.40 Kb.


ABSTRACT

Introduction: ophthalmic emulsion of cyclosporine 0.05% is autoimmune-modulating drug acting as a powerful immune suppressor that prevents epithelial apoptosis and cytokines production.
Objective: to evaluate the effectiveness of an ophthalmic emulsion of cyclosporine 0.05% in patients with dry eye diagnosis treated in the Ophthalmology Service at Hermanos Ameijeiras Clinical-Surgical Hospital.
Methods: descriptive and prospective observational studied in patients who attended the Oculoplastics consultation of the Ophthalmology Service at Hermanos Ameijeiras Clinical-Surgical Hospital from January to December 2012.
Results: an effective response was obtained after one-month treatment with the ophthalmic emulsion of cyclosporine 0.05%, since symptoms and signs reduced considerably and lacrimal production increased, and together with this latter, the time for breaking of the lacrimal film and Schirmer test in 73% of the cases.
Conclusions: the ophthalmic emulsion of cyclosporine 0.05% is an excellent immune-modulating drug which reduces the inflammatory process and increases lacrimal production when it is used for dry eye treatment, which considerably improves the patients’ quality of life.


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