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2015, Number 3

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Rev Cubana Farm 2015; 49 (3)

Biological potential of plants from the genus Bauhinia

de França BI, Ferreira CCH, Calil BJ, Filippin CJ, Damo ML, Palermo MM

Language: English
References: 54
Page: 583-594
PDF size: 126.74 Kb.


ABSTRACT

The genus Bauhinia (Fabaceae, Leguminosae) consists of approximately 300 species, which are commonly known as ‘cow’s paw’ or ‘cow’s hoof’, because of the shape of their leaves. They are widely distributed in most tropical countries, including Africa, Asia and South America. Their leaves and stem-bark have been used frequently in folk medicine as a remedy for different kinds of disease, particularly diabetes, infections, pain and inflammatory processes. Bauhinia longifolia flavonoids demonstrated the highest antiviral activity of all tested substances, being that quercetin had the highest antiviral activity amongst purified flavonoids. The aim of this article is to summarize concisely recent advances published in the last 5 years on the most recent works about the biological activities and phytochemical composition of plants of the genus Bauhinia. For this, was performed a search in some of the databases on the web as PubMed, Google Scholar and Medline, using the keywords Bauhinia, biological properties, diabetes, cancer.


REFERENCES

  1. Ugaz OL. Investigación fitoquímica. Lima: Fondo Editorial de la Pontificia Universidad Católica del Peru; 1994.

  2. Cechinel Filho V, Yunes RA. Estratégias para a obtenção de compostos farmacologicamente ativos a partir de plantas medicinais. Conceitos sobre modificação estrutural para otimização da atividade. Quim Nova. 1998;21(1):99- 105.

  3. Hamburger M, Hostettmann K. Bioactivity in plants: the link between phytochemistry and medicine. Phytochemistry. 1991;30(12):3864-74.

  4. Mitscher LA, Drake S, Gollapudi SR, Okwute SK. A modern look at folkloric use of anti-infective agents. J Nat Prod. 1987;50(6):1025-40.

  5. Cechinel Filho V, Magro JD, Yunes RA. Importância dos estudos químicos e farmacológicos de plantas medicinais brasileiras. Grifos. 1996;3:63-70.

  6. Yunes RA, Pedrosa RC, Cechinel Filho V. Fármacos e fitoterápicos: a necessidade do desenvolvimento da indústria de fitoterápicos e fitofármacos no Brasil. Quim Nova. 2001;24(1):147-52.

  7. Cechinel Filho V. Principais avanços e perspectivas na área de produtos naturais ativos: estudos desenvolvidos no NIQFAR/UNIVALI. Quim Nova. 2000;23(5):680-5.

  8. Lozoya X. Fármacos de origen vegetal de ayer y de hoy. Investig Cienc. 1997;254:4-10.

  9. Yamada CSB. Fitoterapia: sua história e importância. Rev Racine 1998;43:50-1.

  10. Cragg GM, Newman DJ, Snader KM. Natural products in drug discovery and development. J Nat Prod. 1997;60(1):52-60.

  11. da Silva KL, Cechinel Filho V. Plantas do gênero Bauhinia: composição química e potencial farmacológico. Quim Nova. 2002;25(3): 449–54.

  12. Cavalcanti KMPH, Favoretto RF. Bauhinia forficata Link. In: Amaral ACF, Simões EV, Ferreira KLP, eds. Coletânea científica de plantas de uso medicinal. Rio de Janeiro: Fiocruz; 2005. p. 1–17.

  13. Mali RG, Mahajan SG, Mehta AA. Rakta Kanchan (Bauhinia variegata): chemistry, traditional and medicinal uses – a review. Pharmacogn Rev. 2007;1(2):314–19.

  14. Pizzolatti MG, Cunha Junior A, Szpoganicz B, Sousa E, Braz-Filho R, Schripsema J. Flavonóides glicosilados das folhas e flores de Bauhinia forficata (Leguminosae). Quim Nova. 2003;26(4):466-9.

  15. Vaz AMSF, Tozzi AMGA. Sinopse de Bauhinia sect. Pauletia (Cav.) D.C. (Leguminosae: Caesalpinoideae: Cercideae) no Brasil. Rev Bras Bot. 2005;28(3):477-91.

  16. da Cunha AM, Menon S, Menon R, Couto AG, Bürger C, Biavatti MW. Hypoglycemic activity of dried extracts of Bauhinia forficata Link. Phytomedicine. 2010;17(1):37-41.

  17. Martins RE, Castro DM, Castellani DC, Dias JE. Plantas medicinais. Viçosa: Ed. Universidade Federal de Viçosa; 1998.

  18. Menezes FS, Minto ABM, Ruela HS, Kuster RM, Sheridan H, Frankish N. Hypoglycemic activity of two Brazilian Bauhinia species: Bauhinia forficata L. and Bauhinia monandra Kurz. Rev Bras Farmacogn. 2007;17(1):8–13.

  19. Pepato MT, Baviera AM, Vendramini RC, Brunetti IL. Evaluation of toxicity after one-months treatment with Bauhinia forficata decoction in streptozotocin-induced diabetic rats. BMC Complement Altern Med. 2004;4:1-7.

  20. Pepato MT, Keller EH, Baviera AM, Kettelhut IC, Vendramini RC, Brunetti IL. Anti-diabetic activity of Bauhinia forficata decoction in streptozotocin-diabetic rats. J Ethnopharmacol. 2002;81(2):191-7.

  21. Pepato MT, Conceição CQ, Gutierres VO, Vendramini RC, Souza CRF, Oliveira WP, et al. Evaluation of the spouted bed dried leaf extract of Bauhinia forficata for the treatment of experimental diabetes in rats. Afr J Biotechnol. 2010;9(42):7165-73.

  22. da Silva KL, Biavatti MW, Leite SN, Yunes RA, Delle Monache F, Cechinel Filho V. Phytochemical and pharmacognostic investigation of Bauhinia forficata Link (Leguminosae). Z Naturforsch C. 2000;55(5-6):478-80.

  23. Juliani C. Ação hipoglicemiante da unha-de-vaca. Rev Med Pharm Chim Phys. 1929;2(1):165-9.

  24. Juliani C. Ação hipoglicemiante da Bauhinia forficata. Novos estudos experimentais. Rev Sudam Endocrin Immol Quimiot. 1931;14:326-34.

  25. Juliani C. Hypoglycemic action of bauintrato (Bauhinia forficata preparation): new clinical and experimental study. J Clin. 1941;22:17.

  26. Silva FR, Szpoganicz B, Pizzolatti MG, Willrich MA, de Sousa E. Acute effect of Bauhinia forficata on serum glucose levels in normal and alloxan-induced diabetic rats. J Ethnopharmacol. 2002;83(1-2):33-7.

  27. Lino CS, Diógenes JP, Pereira BA, Faria RA, Andrade Neto M, Alves RS, et al. Antidiabetic activity of Bauhinia forficata extracts in alloxan-diabetic rats. Biol Pharm Bull. 2004;27(1):125-7.

  28. Salgueiro ACF, Leal CQ, Bianchini MC, Prado IO, Mendez ASL, Puntel RL, et al. The influence of Bauhinia forficata Link subsp. pruinosa tea on lipid peroxidation and non-protein SH groups in human erythrocytes exposed to high glucose concentrations. J Ethnopharmacol. 2013;148(1):81-7.

  29. Andrade SS, Silva-Lucca RA, Santana LA, Gouvea IE, Juliano MA, Carmona AK, et al. Biochemical characterization of a cysteine proteinase from Bauhinia forficata leaves and its kininogenase activity. Process Biochem. 2011;46(2):572-8.

  30. Ferreres F, Gil-Izquierdo A, Vinholes J, Silva ST, Valentão P, Andrade PB. Bauhinia forficata Link authenticity using flavonoids profile: relation with their biological properties. Food Chem. 2012;134(2):894-904.

  31. Sharon N, Lis H. How proteins bind carbohydrates: lessons from legume lectins. J Agric Food Chem. 2002;50(22):6586-91.

  32. Macedo MLR, Freire MGM, Silva MB, Coelho LC. Insecticidal action of Bauhinia monandra leaf lectin (BmoLL) against Anagasta kuehniella (Lepidoptera: Pyralidae), Zabrotes subfasciatus and Callosobruchus maculates (Coleoptera: Bruchidae). Comp Biochem Physiol A Mol Integr Physiol. 2007;146(4):486–98.

  33. Vaz AMF, Costa RM, Melo AM, Oliva MLV, Santana LA, Silva-Lucca RA, et al. Biocontrol of Fusarium species by a novel lectin with low ecotoxicity isolated from Sebastiania jacobinensis. Food Chem. 2010;119(4):1507-13.

  34. Sharma A, Ng TB, Wong JH, Lin P. Purification and characterization of a lectin from Phaseolus vulgaris cv. (Anasazi Beans). J Biomed Biotechnol. 2009;2009:929568.

  35. Pan S, Tang J, Gu X. Isolation and characterization of a novel fucose-binding lectin from the gill of bighead carp (Aristichthys nobilis). Vet Immunol Immunopathol. 2010;133(2-4):154-64.

  36. Oliveira MD, Andrade CA, Santos-Magalhães MS, Coelho LC, Teixeira JA, Carneiro-da-Cunha MG, et al. Purification of a lectin from Eugenia uniflora L. seeds and its potential antibacterial activity. Lett Appl Microbiol. 2008;46(3):371-6.

  37. Lin P, Ng TB. Preparation and biological properties of a melibiose binding lectin from Bauhinia variegata seeds. J Agric Food Chem. 2008;56(22):10481-6.

  38. Ganguly P, Fossett NG. Inhibition of thrombin-induced platelet aggregation by a derivative of wheat germ agglutinin. Evidence for a physiologic receptor of thrombin in human platelets. Blood. 1981;57(2):343-52.

  39. Nunes BS, Rensonnet NS, Dal-Secco D, Vieira SM, Cavada BS, Teixeira EH, et al. Lectin extracted from Canavalia grandiflora seeds presents potential antiinflammatory and analgesic effects. Naunyn Schmiedebergs Arch Pharmacol. 2009;379(6):609-16.

  40. Silva MCC, Santana LA, Mentele R, Ferreira RS, Miranda A, Silva-Lucca RA, et al. Purification, primary structure and potential functions of a novel lectin from Bauhinia forficata seeds. Process Biochem. 2012;47(7):1049-59.

  41. Silva MCC, de Paula CAA, Ferreira JG, Paredes-Gamero EJ, Vaz AMF, Sampaio MU, et al. Bauhinia forficata lectin (BfL) induces cell death and inhibits integrinmediated adhesion on MCF7 human breast cancer cells. Biochim Biophys Acta. 2014;1840(7):2262-71.

  42. Düsman E, Almeida IV, Coelho AC, Balbi TJ, Tonin LTD, Vicentini VEP. Antimutagenic effect of medicinal plants Achillea millefolium and Bauhinia forficata in vivo. Evid Based Complement Alternat Med. 2013;2013:893050.

  43. Peroza LR, Busanello A, Leal CQ, Röpke J, Boligon AA, Meinerz D, et al. Bauhinia forficata prevents vacuous chewing movements induced by haloperidol in rats and has antioxidant potential in vitro. Neurochem Res. 2013;38(4):789-96.

  44. dos Santos AE, Kuster RM, Yamamoto KA, Salles TS, Campos R, de Meneses MDF, et al. Quercetin and quercetin 3-O-glycosides from Bauhinia longifolia (Bong.) Steud. show anti-Mayaro virus activity. Parasit Vectors. 2014;7:130.

  45. Chandrashekhar KS, Kumar T. Ethnobotany, phytochemical and pharmacological pro􀀀le of Bauhinia purpurea Linn. Res J Med Plant. 2011;5:420-31.

  46. Pattanaik C, Reddy CS, Das R, Reddy M. Traditional medicinal practices among the tribal people of Malkangiri district, Orissa, India. Nat Prod Rad. 2007;6(5):430-5.

  47. Singh M, Singh P. Phytochemical characterization and antibacterial activity of leaf extract of Bauhinia vahlii in Doon Valley, Uttrakhand against human pathogens. The Scitech J. 2014;1(3):20-3.

  48. Nag S, Paul A, Datta RP. Phytochemical analysis of methanolic extract of some medicinal plants. Int J Sci Res Pub. 2013;3(4):1648.

  49. Islam N, Ferdous R, Fahad AB, Hossain MR, Mukti M. In vivo antidiarrheal and in vitro antimicrobial activities of the leaf extracts of Bauhinia acuminata. Am J Res Comm. 2014;2(7):158-68.

  50. Zakaria ZA, Wen LY, Abdul Raman NI, Abdul Ayub AH, Sulaiman MR, Gopalan HK. Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals. Med Princ Pract. 2007;16(6):443-9.

  51. Kamarolzaman MFF, Yahya F, Mamat SS, Jakius KF, Mahmood ND, Shahril MS, et al. Gastroprotective activity and mechanisms of action of Bauhinia purpurea Linn (Leguminoseae) leaf methanol extract. Trop J Pharm Res. 2014;13(11):1889-98.

  52. Kaewamatawong R, Kitajima M, Kogure N, Takayama H. Flavonols from Bauhinia malabarica. J Nat Med. 2008;62(3):364-5.

  53. Thenmozhi K, Karthika K, Manian S, Paulsamy S. Studies on in vitro antioxidant potential of pod and seed parts of Bauhinia malabarica Roxb. Asian J Biomed Pharm Sci. 2014;4(32):48-56.

  54. Sharma M, Neerajarani G, Mujeeb CA, Anu V, Sravan B, Kumar A. Antioxidant, antifungal and phytochemical analysis of Bauhinia malabarica: an in vitro study. Int J Adv Health Sci. 2014;1(6):1-13.




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