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2015, Number 3

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Rev Cubana Farm 2015; 49 (3)

Patient safety in drug therapy for mood disorders

Rodrigues ASA, de Souza RMV, Rodrigues SN, Alves MML, Radighieri RR

Language: Spanish
References: 22
Page: 483-490
PDF size: 69.73 Kb.


ABSTRACT

Introduction: adverse drug reactions are indicators of patient safety, which can cause clinical and economic impacts.
Objective: to describe the adverse drug reactions in patients with mood disorders.
Methods: observational, descriptive, cross-sectional and prospective study, with active search method in pharmacovigilance in patients with mood disorders attended by the Center for Psychosocial Ambulatory Health Care in Brazil from January to July 2011. Patients were invited to participate and answer questions posed in their residences in order to detect the adverse drug reactions and to analyze them in terms of causality and severity.
Results: of 31 patients, 23 presented with 60 adverse drug reactions, being 41.6% probable and 48.3% possible. All the adverse drug reactions were not considered serious, ranging one to five adverse reaction per patient. Of the 16 different medicines used, only bupropion hydrochloride did not present ADR. At least two adverse drug reactions were detected for each medicine.
Conclusion: The active search identified that seven patients out of 10 treated with medicines to control mood disorders, had no serious adverse reaction.


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