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2016, Number 1

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Rev cubana med 2016; 55 (1)

Experience in the treatment of bacterial infection in renal transplant recipients

Cruz ARE, Camacho RSI, Hernández POA, Hernández FME, Batista HR

Language: Spanish
References: 45
Page: 6-19
PDF size: 180.92 Kb.


ABSTRACT

Introduction: renal transplantation is the therapy of choice in the treatment of chronic kidney disease, but specifically bacterial infectious complications maintain high rates of morbidity and mortality and it is a problem difficult to solve. At "Arnaldo Milian Castro" University, eight year-experience has been gained in the treatment of bacterial infection in renal transplant recipients.
Objective: characterize the bacterial infection behavior in renal transplant recipients.
Methods: a descriptive, longitudinal and prospective study was conducted from June 2001 to December 2009, in 102 patients receiving renal transplantation and who were diagnosed with bacterial infections; and 192 bacterial infections confirmed by microbiological education.
Results: nine infectious processes were located in the pulmonary parenchyma with clinic, X-ray images and antimicrobial answer with no positiveness in the specimens gathered and processed in the laboratory. The most affected age group was 31 to 40 years with 32 infectious processes. There were no differences in gender or sex-age relationship. White skin subjects prevailed (74.5 %) (x2 BA = 0.064 p = 0.936). Those who exhibited a single infection were overrepresented (50 %) and urine culture was more positive specimen, 94 for an index of 0.92. Patient groups one and two infectious episodes had 2 deaths each at discharge (p = 0.278). The wound and urinary tract infections prevailed in the immediate postoperative period, with 16 cases, respectively, although the latter was more likely at different evolutive periods. Acinetobacter spp was the most resistant microorganism in urine culture in 3 patients (10.34 %) and the less effective antimicrobial was amoxicillin-sulbactam, in 8 (21.05 %).
Conclusions: the timely and specific selection of the antimicrobial drug at the recommended dose for each patient has been the main tool in our experience.


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