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2016, Number 1

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Rev Cuba Endoc 2016; 27 (1)

Colonization by Candida spp. in diabetic and non-diabetic individuals in the north of Colombia

Suárez ÁP, Llanos GI, Montoya OR, Puello HM, Young CG, Reyes RN

Language: Spanish
References: 46
Page: 59-68
PDF size: 94.69 Kb.


ABSTRACT

Introduction: Candida genus may colonize the human body but also may cause opportunistic infections. Diabetes is frequently considered a risk factor for Candida infections, given its characteristics associated to immunosuppresion, hyperglycemia, microvascularization problems and others. Generally, colonization is necessary for the starting of an infectious process; therefore, it is important to know its frequency of carriage in groups with associated risk factors.
Objective: to determine the percentages of Candida spp. colonization in the oral cavity and the inter-toe area in diabetic and nondiabetic patients.
Methods: the descriptive study was carried out in a group of 85 patients from the north of Colombia, that is, 46 diabetics and 39 non diabetics. The isolates were identified through phenotypical tests including CHROMagar, microscopy, germ tube test, Chlamydospore test and zymogram.
Results: it was found in diabetic patients that the frequency of colonization by Candida spp. in the oral cavity was 23.9 % and in the foot was 56.52 % whereas in non-diabetic patients, the frequency of colonization in the oral cavity was 33.3 % and in the foot was 43.58 %. Additionally, it was found in the group of diabetic subjects that the frequency of colonization by Candida albicans was 45.5 % in the oral cavity whereas that of the foot was 11.5 %.
Conclusions: the achieved results indicate that the local environmental conditions where the Candida spp. is isolated may have an impact on the levels of carriage and the variety of species, which could be more determining than the underlying condition.


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