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Academia Mexicana de Neurología, A.C.

2015, Number 3

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Rev Mex Neuroci 2015; 16 (3)

Executive function, theory of mind and decision making in patients with paranoid schizophrenia stabilized from Peru

Zegarra-Valdivia JA

Language: Spanish
References: 52
Page: 13-26
PDF size: 166.82 Kb.


ABSTRACT

Introduction: The neuropsychological perspective is one of the most influential practices for the study of cognitive deficits in schizophrenia. The development of neuropsychological profiles are especially useful for studying the pathogenesis and rehabilitation of the illness.
Objective: The aim of this study was to evaluate and analyze the performance of subjects with paranoid schizophrenia in several neuropsychological tasks such as executive functioning, theory of mind and decision-making.
Methods: In all, 15 stabilized adults with paranoid schizophrenia (age 34.73 ± 9.32 years), diagnosed with DSM-IV-TR criteria, with a mean of 15.00 ± 9.39 years of disease length compared to 25 healthy adults (age 33.15 ± 11.01 years). The patients were evaluated with the Wisconsin Card Sorting Test, verbal fluency tasks; forward and reverse tasks digit sequence and numbersand- letters of the WAIS-III, Trail Making Test form A and B; and the test of mind reading through the eyes and the IOWA gambling task.
Results: In executive functioning, they showed statistically significant differences for the tasks evaluated, particularly for WCST1 (p‹0.000), the theory of mind (p‹0.001), and the Iowa gambling task (p‹0.001). We found highly significant differences between the domains assessed.
Conclusion: Many differences were observed about their functioning and neuropsychological profile in the domains evaluated between patients and healthy controls. In the group of patients we found failures in these cognitive processes that are of special interest in clinical practice to address its pathogenesis and cognitive rehabilitation.


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