2011, Number 3
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Ann Hepatol 2011; 10 (3)
Clathrin heavy chain (CHC) staining for the diagnosis of small hepatocellular carcinoma
Schaeffer DF, Méndez-Sánchez N
Language: English
References: 6
Page: 374-375
PDF size: 27.41 Kb.
Text Extraction
Original abstract
The American Association for the Study of Liver
Diseases guidelines recommend the use of all available
markers for improving the accuracy of the diagnosis
of small hepatocellular carcinoma (HCC). To
determine whether clathrin heavy chain (CHC), a
novel HCC marker, is effective in combination with
glypican 3 (GPC3), heat shock protein 70, and glutamine
synthetase, we compared the performances of
a three-marker panel (without CHC) and a fourmarker
panel (with CHC) in a series of small HCCs
(≤ 2 cm) and nonsmall HCCs by core biopsy with a
20- to 21-gauge needle.
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