2015, Number 3
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Rev Cub Med Mil 2015; 44 (3)
Application of Atherosclerosis Indexing System in deceased subjects by violent death with coronary aterosclerosis
Hernández PYZ, Fernández-Britto RJE
Language: Spanish
References: 17
Page: 289-300
PDF size: 189.72 Kb.
ABSTRACT
Introduction: the high morbidity and mortality of atherosclerotic causes has motivated multiple investigations and in Cuba, the atherometric system to
characterize atherosclerotic lesions in any vascular sector.
Objective: Study atherosclerosis of the three main coronary vessels in violent deaths from clinical death and comparatively analyzing the injury, considering sex
and level of atherosclerosis.
Methods: Atherometric system was used to comparatively study right and left coronary artery in their anterior descending coronary artery branches and
circumflex, in a population of 108 violently dead subjects and 472 clinical dead subjects, also grouped according to atherosclerotic level and sex.
Results: The main difference was found in fibrous plaques of the atherosclerotic high level group for the right coronary, which reached 22.3% higher in clinical, and only 17.5% for the descending left anterior and 20.3% in the circumflex. In this same group, fibrous plaques were 2.59 times more frequent in the anterior
descending coronary right. Fibrous plaques according to genders had little difference in both groups, only about 1% for the three coronary vessels.
Conclusions: the atherosclerosis is higher clinical dead subjects than violently dead subjects, as much in the overall population, as subdivided in the groups of high and low atherosclerotic level, as in men and women, proving to be the very useful Atherometric System for assessing the atherosclerotic process in violently dead subjects.
REFERENCES
Robbins SL, Cotran RS: Robbins and CotranPathologicBasic of Disease. 9naed: Philadelphia: Elsevier; 2015.
Barrios Grillo E. Aterosclerosis cerebral y sus factores de riesgo en el enfermo mental. Aplicación del Sistema Aterométrico. Rev. Hosp. Psiquiátrico de la Habana. 2012;9(3):10.
Bruetsch WL: The earliest record of sudden death possible due to atherosclerosis coronary occlusion. Circulation. 1959;20:438.
Fernández-Britto JE, Falcón L, Campos R, Guski H, Hufnagl P. Coronary Aterosclerosis in Sudden Death: A Comparative Study Applying an Atherometric System. Gegenbaursmorphol1989. Jahrb. Leipzig 135,1:183-4.
Fernández-Britto JE, Bacallao J. Carlevaro PV, Koch AS, Guski H, Campos R, Falcón L. Atherosclerotic lesion of the circle of Willis: its study applying an Atherometric System using Multivariate Statistical Techniques. Cor Vasa. 1991;33(3):188-96.
MINSAP. Anuario Estadístico [Internet]. 2012. [citado 22 Feb 2014]. Disponible en: http://files.sld.cu/dne/files/2013/04/anuario_2012.pdf
Hernández Puentes Y Z, Campos Peña R, Fernández-Britto Rodríguez JE, Paula Piñera BM, Salinas Olivares M. Caracterización patomorfológica y morfométrica de la lesión aterosclerótica de arterias coronarias en autopsias de fallecidos por muerte violenta. Rev Cub Med Mil. 2010 [citado 22 Feb 2014];39(2):85-94. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138- 65572010000200003&lng=es&nrm=iso&tlng=es
Fernández-Britto, J. E. Atherosclerotic lesion: a Morphometric study applying a biometric system. [dissertation]. Humboldt University of Berlin; 1987.
Holman RL, McGill HC, Strong JP, Geer JC. Technique for studying the atherosclerotic lesions. Lab Invest. 1960;7:42-9.
Fernández-Britto JE, Carlevaro PV. Sistema aterométrico: metodología estandarizada para el estudio de la lesión aterosclerótica y sus consecuencias. Rev Cubana Invest Bioméd. 1988;73:113-23.
Moreno Miravalles MI, Díaz Valdez YN, Paula Piñera BM, Gutiérrez Alba NE, Fernández-Britto JE. Aterosclerosis en autopsiados con cardiopatía isquémica y enfermedad cerebrovascular: aplicación del sistema aterométrico. Rev Cubana Invest Bioméd. 2010;29(2):187-93.
Milei J. Los vasos de neoformación y la producción de hemorragia intraplaca. Rev. Argent. Cardiol. 2012;80(3):8.
Solís Alfonso L, Fernández-Britto JE, Bacallao Gallestey J. Caracterización de la asociación aterosclerosis-osteoporosis en hombres y mujeres: estudio en fallecidos. Rev Cubana Invest Bioméd. 2013;32(3):321-37.
Paula Piñera BM, Díaz Valdés YN, Moreno Miravalles MI, Fernández-Britto JE. Patomorfometría de la aterosclerosis de las coronarias e ilíaco-femorales en fallecidos con antecedentes de diabetes e hipertensión. Rev Cubana Invest Bioméd. 2010;29 (2):170-7.
Alan S. Relation between coronary artery disease, risk factors and intima-media thichness of carotid artery, arterial distensibility and stiffness index. Angiology. May-Jun 2003;54(3):261-7.
Alonso Martínez MI, Ferrer Arocha M, Carballo Martínez R. Factores de riesgo aterosclerótico en familiares de pacientes diabéticos tipo 2. Rev Cubana Invest Bioméd. 2014;33(4):9.
Fernández-Britto Rodríguez JE, Wong Navarro R, Contreras Barrionuevo D, Nordet P, Sternby N: Aterosclerosis en la juventud. Patomorfología y morfometría según edad y sexo, utilizando el sistema aterométrico. Rev Cubana Invest Bioméd. 1998;17(2):128-42.