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2016, Number 1

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Med Crit 2016; 30 (1)

Central venous-arterial CO2 difference as risk factor of death with septic shock

Ocelotl PR, Valle RJ, De Jesús BD, Cortés MJA, Herrera MBE, Mendoza RM

Language: Spanish
References: 31
Page: 30-42
PDF size: 569.13 Kb.


ABSTRACT

Introduction: Severe sepsis and septic shock are a public health problem because of its high prevalence and mortality. The arteriovenous difference of CO2 (DCO2) under physiological conditions does not exceed more than 0.8 kPa (6 mmHg), reflecting adequate venous flow and cardiac output. A macrocirculatorio level there is an inverse relationship between DCO2 and CI in critically ill patients. The aim of this study was to determine the risk of death in the short term DCO2 more than 6 mmHg in patients with septic shock admitted to the intensive care service General Hospital «La Villa» Mexico City.
Material and methods: Longitudinal and descriptive study. We included patients with septic shock at admission, without acute heart failure. Variables: delta CO2; lactate, SvcO2, sites of infection. We analyze the DCO2 › 6 mmHg income at 6 and 12 hours. We obtained relative risk for short-term mortality.
Results: They were 42 patients, 30 men and 12 women, mean age 39 years. Sites of infection: urinary in 18 patients, abdominal at 12, breathing at 6, and soft tissues 6. All patients who died had delta CO2 › 6 mmHg at admission and at 6 hours and 20 patients at 12 hours.
Conclusion: Relative risk of short-term death in patients with DCO2› 6 mmHg is significantly increased when it remains high over time.


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