2016, Number 1
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Med Crit 2016; 30 (1)
Urinary neutrophil gelatinase-associated lipocalin as early biomarker of severe acute kidney injury in Intensive Care
Carrillo ER, Meza MJM, Nava LJA, Zepeda MAD, Díaz CMA, Pérez CÁA
Language: Spanish
References: 20
Page: 10-16
PDF size: 226.16 Kb.
ABSTRACT
Objective: Establish categories of risk for development of severe acute kidney injury based on the combination of levels uNGAL with various clinical variables.
Material and methods: A clinical, retrospective, observational, descriptive and analytical study in the ICU of the Medica Sur Clinic Foundation in understood period of January 1, 2013 to December 31, 2014.
Results: Eighty-two patients included in the study, 37 (45.1%) were male and 45 female (54.9%) with a mean age of 57 ± 20 years. The main cause of admission was septic shock in 57.3%. Creatinine levels and time uresis uNGAL significant differences with a probability less than 0.05. The cutoff for the diagnosis of acute kidney injury admission was 166.8 ng/mL, and the outcome of severe acute kidney injury, the income cutoff was 306.35 ng/mL.
Conclusions: There was no statistically significant difference between variables except for the creatinine levels and urinary lipocalin uresis time. Cutting uNGAL admission to the outcome of severe AKI was 306.35 ng/mL.
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