2016, Number 2
<< Back Next >>
Ann Hepatol 2016; 15 (2)
Cystic angiosarcoma of the liver. A previously undescribed neoplasm
Cano-García F, Athie-Athie AJ, García-Gómez JI, Chablé-Montero F, Albores-Saavedra J
Language: English
References: 20
Page: 283-286
PDF size: 232.69 Kb.
ABSTRACT
We report an example of a cystic hepatic angiosarcoma that to our knowledge has not been previously described. The patient was a
70 year old woman who was admitted to the emergency room because of hypovolemic shock. A computed tomography showed four
heterogeneous hepatic cystic masses varying from 2.5 to 11.2 cm; one of these with rupture and formation of a subcapsular hematoma.
The cyst wall was lined by several layers of neoplastic epithelioid and spindle shaped endothelial cells that in some areas extended
to the underlying stroma. They expressed CD31 and CD34, and were negative for cytokeratin. The patient is alive with residual
hepatic cystic angiosarcoma. However, follow up is too short to be significant.
REFERENCES
Albores-Saavedra J, Schwartz AM, Henson DE, Kostun L, Hart A, Angeles Angeles D, Chablé Montero F. Cutaneousangiosarcoma. Analysis of 434 cases from the Surveillance, Epidemiology, and End Results Program, 1973-2007. Ann DiagnPathol 2011; 15: 93-7.
Maddox JC, Evans HL. Angiosarcoma of skin and soft tissue: a study of forty-four cases. Cancer 1981;48: 1907-21.
Meiss-Kindblom JM, Kindblom LG. Angiosarcoma of soft tissue: a study of 80 cases. Am J Surg Pathol 1998; 22: 683- 97.
Falk H, Herbert J, Crowley S, Ishak KG, Thomas LB, Popper H, Caldwell GG. Epidemiology of Hepatic Angiosarcoma in the United States: 1964-1974. Environ Health Perspect 1981; 41: 107-13.
Groeschl RT, Miura JT, Oshima K, Gamblin TC, Turaga KK. Does Histology Predict Outcome for Malignant Vascular Tumors of the Liver?J Surg Oncol 2014; 109: 483-6.
Duan XF, Li Q. Primary hepatic angiosarcoma: a retrospective analysis of 6 cases. JDig Dis 2012; 13: 381-5.
Fayette J, Martin E, Piperno-Neumann S, Le Cesne A, Robert C, Bonvalot S, Ranchère D, et al. Angiosarcomas, a heterogeneous group of sarcomas with specific behavior depending on primary site: a retrospective study of 161 cases. Ann Oncol 2007; 18: 2030-6.
Egea Valenzuela J, López Poveda MJ, Pérez Fuenzalida FJ, Garre Sánchez C, Martínez Barba E, Carballo Álvarez F. Hepaticangiosarcoma. Presentation of two cases. Rev Esp Enferm Dig 2009; 101: 430-7.
Yang KF, Leow VM, HasnanMN, Manisekar KS. Primary Hepatic Angiosarcoma: Difficulty in Clinical, radiological, and pathological diagnosis. Med J Malaysia 2012; 67: 127-8.
Locker GY, Doroshow JH, Zwelling LA, Chabner BA. The clinical features of hepatic angiosarcoma: a report of four cases and a review of the English literature. Medicine (Baltimore) 1979; 58: 48-64.
Naka N, Ohsawa M, Tomita Y, Kanno H, Uchida A, Aozasa K.Angiosarcoma in Japan. A review of 99 cases. Cancer 1995; 75: 989-96.
Abegunde AT, Aisien E, MbA B, Chennuri R, Sekosan M. Fulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma. Case Rep Gastrointest Med 2015. Article ID 869746, 8 pages.
Sung JY, Ahn S, Kim SJ, Park YS, Choi YL. Angiosarcoma arising within a long-standing cystic lesion of the adrenal gland: a case report. J Clin Oncol 2013; 31: 132-6.
Geramizadeh B, Safari A, Bahador A, Nikeghbalian S, Salahi H, Kazemi K, Dehghani SM, et al. Hepatic angiosarcoma of childhood: a case report and review of literature. J Pediatr- Surg 2011; 46: E9-E11.
Ho SY, Tsai CC, Tsai YC, Guo HR. Hepatic angiosarcoma presenting as hepatic rupture in a patient with long-term ingestion of arsenic. J Formos Med Assoc 2004; 103: 374-9.
Weitz J, Klimstra DS, Cymes K, Jarnagin WR, D’Angelica M, La Quaglia MP, Fong Y, et al. Management of primary liver sarcomas.Cancer 2007; 109: 1391-6.
Kim HR, Rha SY, Cheon SH, Roh JK, Park YN, Yoo NC. Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma.Ann Oncol 2009; 20: 780-7.
Park YS, Kim JH, Kim KW, Lee IS, Yoon HK, Ko GY, Sung KB. Primary hepatic angiosarcoma: imaging findings and palliative treatment with transcatheter arterial chemoembolization or embolization. ClinRadiol 2009; 64: 779-85.
Cazorla A, Félix S, Delabrousse E, Valmary-Degano S. Primary hepatic angiosarcoma: A retrospective analysis of eight cases. Ann Pathol 2014, 34: 462-8.
Chi TY, Yang ZY, Xue HD, Lü K, Feng RE, Xu HF, Yang XB. Diagnosis and treatment of primary hepatic angiosarcoma: a report of 7 cases with a literature review. Zhonghua Yi Xue- ZaZhi 2011; 91: 1694-7.