Vargas-Lares JJ, Andrade-Aguilera AR, Díaz-Peña R, Barrera de LJC

Language: Spanish
References: 22
Page: 749-756
PDF size: 89.57 Kb.

ABSTRACT

Objective: To determine risk factors associated with bacterial growth in systems derived from cerebrospinal fluid in pediatric patients. Methods: Case and controls study from January to December 2012, in patients aged ‹ 16 years who were carriers of hydrocephalus and who required placement or replacement of derivative system. Cases were considered as children with cultures with bacterial growth and controls with negative bacterial growth. Inferential statistics with Chi-squared and Mann- Whitney U tests. Association of risk with odds ratio. Results: We reviewed 746 registries, cases n = 99 (13%) and controls n = 647 (87%). Masculine gender 58 (57%) vs. feminine gender 297 (46%) (p = 0.530). Age of cases: median, five months and controls, one year (p = 0.02). Median weight, 7 vs. 10 kg (p = 0.634). Surgical interventions: median n = 2 (range, 1-8) vs. n = 1 (range, 1-7). Infection rate, 13.2%. Main etiology ductal stenosis, n = 29 (29%) vs. n = 50 (23%) (p = 0.530). Noncommunicating, n = 50 (51%) vs. 396 (61%) (p = 0.456). Predominant microorganisms: enterobacteria, pseudomonas, and enterococcus. Non-use of iodized dressing OR = 2.6 (range, 1.8-4.3), use of connector OR = 6.8 (range, 1.9-24.0), System replacement OR = 2.0 (range, 1.3-3.1), assistant without surgical facemask OR = 9.7 (range, 2.3-42.0). Conclusions: Being a breastfeeding infant, of low weight, non-application of iodized dressing, use of connector, previous derivation, and lack of adherence to aseptic technique were all factors associated with ependymitis.

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