2015, Number 4
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Dermatología Cosmética, Médica y Quirúrgica 2015; 13 (4)
Blue man syndrome associated to retigabine drug: a case report
Pérez-Lizárraga RI, Hernández-Collazo AA, Hernández-Arana MS
Language: Spanish
References: 14
Page: 331-334
PDF size: 148.29 Kb.
ABSTRACT
Previously known as blue man syndrome, to the diffuse bluegray
dyschromia caused by chronic silver exposure. Currently,
there are other entities that cause this syndrome, like some
drugs. Recently reported adverse event of retigabine (ezogabine),
characterized by changes in pigmentation of skin, nails
and retina, also known as blue man syndrome. Despite that
the mechanism of these pigment changes have not been determined,
it is well known the potential reversibility of the dyschromia.
The Food and Drug Administration of the United
States (fda) has issued an alert, forcing to place a label informing
about the risk for retinal and skin pigmentation.
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