2012, Number 4
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MEDICC Review 2012; 14 (4)
Acute myocardial infarction mortality in Cuba, 1999–2008
Armas NB, Ortega YY, de la Noval R, Suárez R, Llerena L, Dueñas AF
Language: English
References: 53
Page: 19-25
PDF size: 147.23 Kb.
ABSTRACT
Introduction: Acute myocardial infarction is one of the leading causes of death in the world. This is also true in Cuba, where no national-level epidemiologic studies of related mortality have been published in recent years.
Objetive: Describe acute myocardial infarction mortality in Cuba from 1999 through 2008.
Methods: A descriptive study was conducted of persons aged ≥ 25 years with a diagnosis of acute myocardial infarction from 1999 through 2008. Data were obtained from the Ministry of Public Health's National Statistics Division database for variables: age; sex; site (out of hospital, in hospital or in hospital emergency room) and location (jurisdiction) of death. Proportions, age- and sex-specific rates and age-standardized overall rates per 100,000 population were calculated and compared over time, using the two five-year time frames within the study period.
Results: A total of 145,808 persons who had suffered acute myocardial infarction were recorded, 75,512 of whom died, for a case-fatality rate of 51.8% (55.1% in 1999–2003 and 49.7% in 2004–2008). In the first five-year period, mortality was 98.9 per 100,000 population, falling to 81.8 per 100,000 in the second; most affected were people aged ≥ 75 years and men. Of Cuba's 14 provinces and special municipality, Havana, Havana City and Camagüey provinces, and the Isle of Youth Special Municipality showed the highest mortality; Holguín, Ciego de Ávila and Granma provinces the lowest. Out-of-hospital deaths accounted for the greatest proportion of deaths in both five-year periods (54.8% and 59.2% in 1999–2003 and 2004–2008, respectively).
Conclusions: Although risk of death from acute myocardial infarction decreased through the study period, it remains a major health problem in Cuba. A national acute myocardial infarction case registry is needed. Also required is further research to help elucidate possible causes of Cuba's high acute myocardial infarction mortality: cardiovascular risk studies, studies of out-of-hospital mortality and quality of care assessments for these patients.
REFERENCES
Life tables for WHO Member States [Internet]. Geneva: World Health Organization; 2006 [cited 2010 Aug 16]. Available from: http:// www.who.int/healthinfo/statistics/mortality_life _tables/en/
Statistical Fact Sheet — Populations 2007 Update International Cardiovascular Disease Statistics [Internet]. Dallas (US): American Heart Association; 2007 [cited 2010 Aug 16]. 10 p. Available from: http://www.heartplus.co.za/down loads/heartworldfactsheet.pdf
Sachs J. A Race against Time. The Challenge of Cardiovascular Disease in Developing Economies [Internet]. New York: Columbia University; 2004 [cited 2012 August 21]. 54 p. Available from: http://www.earth.columbia.edu/news/2004/ images/raceagainsttime_FINAL_051104.pdf
Heart and Stroke Foundation of Canada [Internet]. Ontario: Heart and Stroke Foundation of Canada; c2012. 2004 Quick Facts; 2004 [cited 2010 Aug 16]; [about 2 screens]. Available from: http://www.heartandstroke.com/site/apps/nlnet/ content2.aspx?c=ikIQLcMWJtE&b=4955951& ct=4512817
CDC. Health, United States, 2007 With Chartbook on Trends in the Health of the Americans. Hyattsville (US): National Center for Health Statistics; 2008 Feb. 572 p.
Smolina K, Wright FL, Rayner M, Goldacre MJ. Determinants of the decline in mortality from acute myocardial infarction in England between 2002 and 2010: linked national database study. BMJ. 2012 Jan 25;344:d8059.
Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, DeSimone G, et al. Heart Disease and Stroke Statistics — 2010 Update: A Report from the American Heart Association. Circulation [Internet]. 2010 Feb 23 [cited 2012 Jan 25];121(7):e46–e215. Available from: http://circ .ahajournals.org/content/121/7/e46.full.pdf.html
Levi F, Lucchini F, Negri E, La Vecchia C. Trends in mortality from cardiovascular and cerebrovascular diseases in Europe and other areas of the world. Heart. 2002 Aug;88(2):119–24.
Cardiovascular Disease in England: Opportunities and Challenges Over the Next Ten Years [Internet]. London: British Heart Foundation; 2008 Apr [cited 2010 Aug 16]. 86 p. Available from: http://www.bhf.org.uk/cvc/pdf/ CVC_10Years_2008_v2.pdf
Müller-Nordhorn J, Binting S, Roll S, Willich SN. An update on regional variation in cardiovascular mortality within Europe. Eur Heart J. 2008 May;29(10):1316–26.
Boix Martínez R, Aragonés Sanz N, Medrano Albero MJ. Tendencias en la mortalidad por cardiopatía isquémica en 50 provincias españolas. Centro Nacional de Epidemiología. Instituto de Salud Carlos III. Madrid, España. Rev Española Cardiol. 2003;56(9):850–6. Spanish.
American Heart Association. Heart Disease and Stroke Statistics. Our guide to current statistics and the supplement to our Heart & Stroke Facts. 2010 Update At-A-Glance. Circulation [Internet]. 2009 Dec [cited 2011 Feb 2]. Available from: http://circ.ahajournals.org/cgi/reprint/ CIR.0b013e3182009701
Velázquez Ó, Barinagarrementería FS, Rubio AF, Verdejo J, Méndez MA, Violante R, et al. Morbilidad y mortalidad de la enfermedad isquémica del corazón y cerebrovascular en México. 2005. Arch Cardiol Méx [Internet]. 2007 Jan–Mar [cited 2010 Aug16];77(1):31–9. Available from: http://www.scielo.org.mx/scielo.php?pid=S1405 -99402007000100005&script=sci_arttext. Spanish.
Rosas-Peralta M, Attie F. Enfermedad cardiovascular. Primera causa de muerte en adultos de México y el mundo. Arch Cardiol Mex. 2007 Apr–Jun;77(2):91–3. Spanish.
Roselló M, Guzmán S. Evolución de la mortalidad por enfermedad isquémica del corazón e infarto agudo del miocardio en Costa Rica, 1970–2001. Rev Panamericana Salud Púb. 2004;16(5):295– 301. Spanish.
Avezum A, Braga J, Santos I, Guimaraes HP, Marín JA, Piegas LS. Cardiovascular disease in South America: Current status and opportunities for prevention. BMJ. 2009 Feb 17;95:1475–82.
Kauffmann QR. Infarto agudo del miocardio: el factor tiempo. Rev Med Chil. 2008 Sep;136(9):1095–7. Spanish.
Wainstein R, Furtado MV, Polanczyk CA. Prehospital thrombolysis in AMI: a feasible alternative to Brazil. Arq Bras Cardiol. 2008 Feb;90(2):71–3. Spanish, Portuguese.
Montes de Oca ZS. Alfi nal.com [Internet]. Venezuela: AlFinal.com; c2012; Comportamiento del Infarto Agudo del Miocardio en el Municipio Pedro María Ureña. Venezuela 07/2005–12/2006; [cited 2011 Jun 10]. Available from: http://www .alfi nal.com/Cuba/infartoagudo.shtml. Spanish.
Jorna AR, Véliz PL, Cuéllar R. [Myocardial acute infarction in integral diagnosis centers of Vargas, Venezuela]. Rev Cubana Med Gen Integr [Internet]. 2010 Oct–Dec [cited 2012 Sep 12];26(4):712–20. Available from: http://scielo .sld.cu/pdf/mgi/v26n4/mgi14410.pdf. Spanish
Delgado A, Fagundo F, López E, Valdés C, Salabert I. Transición epidemiológica. Rev Medica Electron [Internet]. 2003 Jan–Feb [cited 2011 Jun 10];25(1). Available from: http://www.revmatan zas.sld.cu/revista%20medica/ano%202003/ vol1%202003/tema03.htm. Spanish.
Anuario Estadístico de Salud 2010 [Internet]. Havana: Ministry of Public Health (CU); 2011 Apr [cited 2011 May 28]. 174 p. Available from: http:// fi les.sld.cu/dne/fi les/2011/04/anuario-2010-e-sin -grafi cosl.pdf. Spanish.
Fernández A, Gálvez AM, Castillo A. Costo institucional del infarto agudo del miocardio en el Instituto de Cardiología y Cirugía Cardiovascular. Rev Cubana Salud Pública. 2008 Oct– Dec;34(4):27–56. Spanish.
García A, García ME, Quiñones A, Chávez E, Cañedo O. Impacto del sistema integral de urgenc ias médicas en la mortalidad por infarto miocárdico agudo. Rev Cubana Med Int Emerg. 2006;5(1):312–6. Spanish.
Sosa A. Terapia intensiva. Havana: Editorial Ciencias Médicas; c2006. Volume 1, Chapter 3, Organización y dirección de la urgencia y los cuidados intensivos. Spanish.
International classifi cation of diseases. 9th rev. Geneva: World Health Organization; 1977.
International statistical classifi cation of diseases and related health problems. 10th rev. Geneva: World Health Organization; 1992.
National Bureau of Medical Records and Health Statistics (CU). Estadísticas de Salud [Internet]. Havana: Ministry of Public Health (CU); c2012. Dirección Nacional de Registros Médicos y Estadísticas de Salud del Ministerio de Salud Pública (DNE-MINSAP).1970–2005; 2006 [cited 2010 May 28]. Available from: http:// www.sld.cu/sitios/dne/temas.php?idv=4022. Spanish.
Quantitative Micro Software, LLC. EViews 4 User’s Guide [Internet]. 2002 Mar [cited 2010 May 8. p 190–7. Available from: http://www.nek .lu.se/nekded/Teaching/Econometrics_IUsers _Guide_4_0.pdf
Defunciones según la causa de muerte 2002. Madrid: Instituto Nacional de Estadística; 2005. Spanish.
Lanas F, Avezum A, Bautista LE, Díaz R, Luna M, Islam S, et al. INTERHEART Latin American Study Risk Factors for Acute Myocardial Infarction in Latin America. Circulation. 2007 Mar 6;115(9):1067–74.
Buzzi A. Fisiopatología Cardiovascular: Bases racionales para la terapéutica. Rev Argentina Cardiol [Internet]. 2010 Nov–Dec [cited 2011 Sep 6];78(6):521. Available from: http://www.scielo.org.ar/ scielo.php?script=sci_arttext&pid=S1850 -37482010000600014&lng=es. Spanish.
Blanco P, Gagliardi J, Higa C, Dini A, Guetta J, Di Toro D. Infarto agudo de miocardio. Resultados de la Encuesta SAC 2005 en la República Argentina por los Investigadores del Área de Investigación SAC y el Consejo de Emergencias Cardiovasculares de la SAC. Rev Argent Cardiol. 2007 May–Jun;75(3):29– 49. Spanish.
Gagliardi J, Charask A, Higa C, Blanco P, Dini A, Tajer C, et al. Infarto agudo de miocardio en la República Argentina. Análisis comparativo de sus características y conductas terapéuticas en los últimos 18 años. Resultados de las Encuestas SAC. Rev Argent Cardiol. 2007;75(3):125. Spanish.
Ortega Torres Y, Armas Rojas N, de la Noval García R, Castilla Arocha I, Suárez Medina R, Feliciano Dueñas A. Incidencia del infarto agudo de miocardio. Rev Cubana Invest Bioméd. 2011;30(3):345–53. Spanish.
Armas Rojas N, Ortega Torres Y, de la Noval García R, Suárez Medina R, Llerena Rojas L, Dueñas Herrera A. Letalidad por infarto agudo de miocardio en Cuba, 1999–2008. Rev Cubana Cardiol Cir Cardiovasc. 2011;17(1):4–10. Spanish.
Ordúñez P, Cooper RS, Espinosa AD, Iraola MD, Bernal JL, La Rosa Y. Enfermedades cardiovasculares en Cuba: determinantes para una epidemia y desafíos para la prevención y control. Rev Cubana Salud Pública. 2005;31(4):270–84. Spanish.
Truelsen T, Mähönen M, Tolonen H, Asplund K, Bonita R, Vanuzzo D, et al. Trends in Stroke and Coronary Heart Disease in the WHO MONICA Project. Stroke. 2003 Jun;34(6):1346–52.
Sans S, Puigdefábregas A, Paluzie G, Monterde D, Balaguer-Vintró I. Increasing trends of acute myocardial infarction in Spain: the MONICA-Catalonia Study. Eur Heart J. 2005 Mar;26(5):505–15.
Rosamond WD, Folsom AR, Chambless LE, Wang CH; ARIC Investigators. Atherosclerosis Risk in Communities. Coronary heart disease trends in four United States communities. The Atherosclerosis Risk in Communities (ARIC) Study 1987–1996. Int J Epidemiol. 2001 Oct;30 Suppl 1:S17–22.
Tunstall-Pedoe H, Vanuzzo D, Hobbs M, Mähönen M, Cepaitis Z, Kuulasmaa K, et al. Estimation of contribution of changes in coronary care to improving survival, event rates, and coronary heart disease mortality across the WHO MONICA Project populations. Lancet. 2000 Feb 26;355(9205):688–700.
Buiatti E, Barchielli A, Marchionni N, Balzi D, Carrabba N, Valente S, et al. Determinants of treatment strategies and survival in acute myocardial infarction: a population-based study in the Florence district, Italy: results of the acute myocardial infarction Florence registry (AMI-Florence). Eur Heart J. 2003 Jul;24(13):1195–203.
Spencer FA, Montalescot G, Fox KA, Goodman SG, Granger CB, Goldberg RJ, et al. Delay to reperfusion in patients with acute myocardial infarction presenting to acute care hospitals: an international perspective. Eur Heart J. 2010 Jun;31(11):1328–36.
Kesteloot H, Sans S, Kromhout D. Dynamics of cardiovascular and all-causes mortality in Western and Eastern Europe between 1970–2000. Eur Heart J. 2006 Jun;27(1):107–13.
Vega G, Martínez S, Jiménez PA, Navarro A, Bernad F. Efecto de los factores de riesgo cardiovascular sobre la morbimortalidad a largo plazo después de un infarto agudo de miocardio. Rev Esp Cardiol. 2007 Jul;60(7):703–13. Spanish.
Debs Pérez G, de la Noval García R, Dueñas Herrera A, Debs Pino JG. ¿Aumentan los Factores de Riesgo coronario el riesgo de muerte después de cinco años? Rev Cubana Cardiol Cir Cardiovasc. 2001;15(1):6–13. Spanish.
Medrano MJ, Boix R, Cerrato E, Ramírez M. Incidencia y prevalencia de cardiopatía isquémica y enfermedad cerebrovascular en España: Revisión sistemática de la literatura. Rev Esp Salud Pública. 2006 Jan–Feb;80(1):5– 15. Spanish.
II Encuesta Nacional de Factores de Riesgo de Enfermedades Crónicas no Transmisibles en Cuba. Informe de Trabajo. Havana: National Hygiene, Epidemiology and Microbiology Institute (CU); 2002. Spanish.
Gabán AM, Alegrant FL, Cardoso EC. Biblioteca Virtual de Salud [Internet]. Havana: National Medical Sciences Information Center (CU); c2012. Comportamiento del infarto agudo del miocardio en la Unidad de Cuidados Intensivos emergentes; 2005 [cited 2012 Feb 12]; [about 3 screens]. Available from: http://www.bvs.sld.cu/revistas/mciego/ vol11_supl2_05/articulos/a8_v11_supl205 .htm. Spanish.
Gómez MV, Herrera ML, Ladaga HG, Cabrera I. Trombolisis en el infarto agudo del miocardio. Epidemiología de los tiempos de demora. Rev Cubana Med. 2002 Sep–Oct;41(5):91–5. Spanish.
Cáceres–Lóriga FM. History of Streptokinase use in Acute Myocardial Infarction. Tex Heart Inst J [Internet]. 2008 [cited 2011 Jun 10];35(1):91. Available from: http://www.ncbi.nlm.nih.gov/pmc/ articles/PMC2322881/pdf/20080300s00032p91 .pdf
TERIMA Group of Investigators. TERIMA-2: national extension of thrombolytic treatment with recombinant streptokinase in acute myocardial infarct in Cuba. Thromb Haemost. 2000 Dec;84(6):949–54.
Castillo B, Campusano A, Hernández W, Trueba D, López M, Morejón D. Trombolisis: aplicación, posibilidad e inconvenientes. Rev Cub Med Int Emerg. 2007 [cited 2011 Jun 10];6(3):768–78. Available from: http://bvs.sld.cu/revistas/mie/ vol6_3_07/mie01307.htm. Spanish.