2015, Number 2
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Rev Invest Clin 2015; 67 (2)
Changes in Frequency of Delayed Graft Function in Deceased Donor Renal Transplant Recipient in a Tertiary Care Center in Mexico
Noriega-Salas AL, Alberú J, Sánchez-Cedillo AI, Navarro-Vargas L, Visag V, Vintimilla-Moscoso A, López-Jiménez JL, Madrigal-Bustamante J, Contreras AG, Vilatobá-Chapa M
Language: English
References: 24
Page: 89-97
PDF size: 186.62 Kb.
ABSTRACT
Background: Delayed graft function (DGF) is defined as the need for dialysis within the first seven days of transplantation. The
frequency of DGF has decreased in the last five years compared with the previous 20 years of the kidney transplant program at
a Mexican referral hospital.
Objective: To determine the incidence and risk factors for DGF in the past five years (2009-2013).
Methods: We analyzed a retrospective cohort of renal transplant recipients from deceased donors at our hospital between
March 2009 and May 2013 (Period 2), and compared the results with a previously evaluated cohort (Period 1, between January
1990 and February 2009).
Results: During the analyzed period, 78 deceased donor transplants were performed. The frequency
of DGF was 9%. Multivariate analysis showed that recipient older age (OR: 1.074419; 95% CI: 1.0009-1.155116; p = 0.05),
transoperative amines administration (OR: 7.73; 95% CI: 1.037-57.6; p = 0.046), and hypotension during surgery in the recipient
(OR: 11.6; 95% CI: 1.33-100.8; p = 0.026) were risk factors for DGF.
Conclusion: The incidence of DGF has significantly
decreased in the past five years when compared to the previous 20 years in our hospital.
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