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2003, Number 3

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Cir Cir 2003; 71 (3)

Innate immunity, Toll receptor and sepsis

Carrillo-Esper R

Language: Spanish
References: 89
Page: 252-258
PDF size: 109.35 Kb.


ABSTRACT

The innate immune response is the first line of defense against infection. Toll-like receptors (TLRs) recognize bacterial lypopolysaccharide and other pathogen-associated molecular patterns (PAMPs). Intracellular signals initiated by interaction between Toll receptors and specific PAPMs results in inflammatory response. Sepsis and septic shock are the result of an exaggerated inflammatory systemic response induced by innate immune dysregulation.


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