2015, Number 4
Púrpura de Schönlein-Henoch fulminante
Language: Spanish
References: 9
Page: 102-111
PDF size: 248.71 Kb.
ABSTRACT
A female patient of 51 years old with personal pathological precedent of bronchial asthma, hypertension and ulcerative colitis and infection by chikungunya virus for a month. She incomes with dark pasty diarrhea with mucus and blood, she evolved unfavorably with flaccid paraplegia and recticularis livedo, which became extensive purple; then phlyctena and generalized edema. She remained hypotensive with electrolyte imbalance and impairment of consciousness, complementaries were performed, she was transfused and underwent to hemodialysis; she evolved to coma and death. The pathological findings showed an adult, fulminant and deadly form of anaphylactoid purpura or Henoch-Schönlein. Mesangial proliferation with fushinofílicos mesangial deposits werefound corresponding to immunoglobulin A with immunofluorescence, leukocytoclastic vasculitis and necrotizing vasculitis of small vessels. Purple of Schönlein-Henoch is a peculiar form of vasculitis that tends to spontaneous healing and occasionally may have a fatal course or proceed to a chronic nephritis.REFERENCES
Mao S, Xuan X, Sha Y, Zhao S, Zhu C, Zhang A, et al. Clinico-pathological association of Henoch-Schoenlein purpura nephritis and IgA nephropathy in children. Int J Clin Exp Pathol [Internet]. 2015 Mar 1 [citado 15 Abr 2015];8(3):6. Sotoodian B, Robert J, Mahmood MN, Yacyshyn E. IgA cutaneous purpura post-renal transplantation in a patient with long-standing IgA nephropathy: case report and literature review. J Cutan Med Surg [Internet]. 2015 Sep-Oct [citado 19 Nov 2015];19(5):498-503. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/25876643
Paydary K, Emamzadeh Fard S, Mahboubi AH, Ziaee V, Moradinejad MH, et al. Penile skin involvement as the first presentation of Henoch-Schonlein Purpura. Report of nine cases and review of literature. Iran J Pediatr [Internet]. 2015 Agos [citado 15 Oct 2015];25(4):e2177. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/26396696