2015, Number 6
<< Back Next >>
Rev Med Inst Mex Seguro Soc 2015; 53 (6)
Intrarectal povidone-iodine to reduce the risk of genitourinary infections after transrectal prostate biopsy
Moreno-Palacios J, Espinosa-Guerrero A, Torres-Anguiano JR, Montoya- Martínez G, López-Samano V, Serrano-Brambila E
Language: Spanish
References: 23
Page: 728-731
PDF size: 307.40 Kb.
ABSTRACT
Background: The aim of this study is to compare two different preparations
in patients undergoing transrectal prostate biopsies samples
(TPBS) and assess the prevalence of genitourinary infections (GUI).
Methods: A historical cohort of patients undergoing TBPS for suspected
prostate cancer. Two groups were compared: one with endorectal lubricant
jelly and another with the addition of a povidone-iodine lubricating
jelly. Complications were evaluated at three weeks. A bivariate analysis
was performed by calculating the OR (95 % CI) to determine if the
additional endorectal povidone-iodine pre-TBPS reduced GUI and other
complications.
Results: 185 patients (Group I
n = 86, Group II
n = 96) were evaluated. 45
and 25 % had genitourinary tract infection (OR: 0.4, CI: 0.2-0.9,
p = 0.004);
fever was presented in 21 and 10 % respectively (OR: 0.42, CI: 0.1-0.9,
p = 0.04).
Conclusions: A reduction was observed in the presence of genitourinary
infections in patients who had intrarectal povidone-iodine preparation
applied.
REFERENCES
Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin 2014;64:9-29.
Herranz-Amo F, Díez-Cordero JM, Cabello-Benavente R. Evolución de la Técnica de Biopsia Transrectal Ecodirigida de la Próstata. Arch. Esp. Urol. 2006; 59 (4):385-396.
Levine MA, Ittman M, Melamed J, Lepor H. Two consecutive sets of transrectal ultrasound guided sextant biopsies of the prostate for the detection of prostate cancer. J Urol 1998;159(2):471-5.
Djavan B, Waldert M, Zlotta A, Dobronski P, Seitz C, Remzi M, et al.: Safety and morbidity of first andrepeat transrectal ultrasound guided prostate needle biopsies: Results of a Prospective European Prostate Cancer Detection Study. J Urol. 2001;166 (2):856-60.
Pepe P, Aragona F.: Morbidity after transperineal prostate biopsy in 3000 patients Undergoing 12 vs 18 vs more than 24 needle cores. J. Urol.2013;81(6):1142-6.
Collins GN, Lloyd SN, Hehir M. McKelvie GB: Multiple transrectal ultrasound guided prostatic biopsies— true morbidity and patient acceptance. Br J Urol.1993;71(4):460-3.
Loeb S, Carter HB, Berndt SI, Ricker W, Schaeffer EM. Complications after prostate biopsy Data from Seer-Medicare. J Urol. 2001;186(5):1830-1834.
Zayotoun OM, Anil T, Moussa AS, Jianabo L, Fareed K, Jones JS. Morbidity of prostate biopsy after simplified versus complex preparation protocols: assessment of risk factors. Urology 2011;77(4):910-4.
Carey JM, Korman HJ. Transrectal ultrasound guided biopsy of the prostate. Do enemas decrease clinically sifnificant complications?. J Urol.2001;166(1):82-85.
Abughosh Z, Margolick J, Goldenberg SL, Taylor SA, Afshar K, Bell R et al.: A prospective randomized trial of povidone-iodine prophylactic cleansing of the rectum before transrectal ultrasound guided prostate biopsy. J Urol 2013;189(5):1326-31.
Gil-Vernet Sedo JM, Alvarez-Vijande García R. Effect of intrarectal povidone-iodine in the incidence of infectious complications after transrectal prostatic biopsy. Arch. Esp. Urol.2012;65(4):463-466.
Ghafoori M, Shakiba M, Seifmanesh H, Hoseini K. Decrease in infection rate following use of povidoneiodine during transrectal ultrasound guided biopsy of the prostate: a double blind randomized clinical trial. Iran J Radiol. 2012; 9(2):67-70.
Kanjanawongdeengam P, Viseshsindh W, Santanirand P, PrathombutrP, Nilkulwattana S. Reduction in bacteremia rates after rectum sterilization before transrectal, ultrasound-guided prostate biopsy: a randomized controlled trial. J Med Assoc Thai.2009;92(12):1621-6.
Rees M. Povidone-iodine antisepsis for transrectal prostatic biopsy. Br Med J. 1980;281(6241):650.
Lachapelle JM, Castel O, Fueyo Casado A, Leroy B, Micali G, Tennstedt D, et al. Antiseptics in the era of bacterial resistance: a focus on povidone iodine. Clin Pract. 2013;10(5):579-592.
Pu Ch, Bai Y, Yuan H, Li J, Tang Y, Huang J et al. Reducing the risk of infections for transrectal prostate biopsy with povidone-iodine: a systematic review and meta-analysis. Int Urol Nephrol 2014;46:1691-1698.
Park DS, Oh JJ, Lee JH, Jang Wk, Hong YK, Hong SK. Simple use of the suppository type povidone-iodinecan prevent infectious complications in transrectal ultrasound-guided prostate biopsy. Adv Urol2009; Article ID 750598, 4 pages. Doi:10.1155/2009/750598.
Liss MA, Nakamura KK, Meuleners R, Kolla SB, Dash A, Pterson EM. Screening rectal culture to identify fluoroquinolone-resistant organisms before transrectal prostate biopsy: do the culture results between office visit and biopsy correlate?. Urology.2013;82(1):67-71
Batura D, Rao GG, Nielsen PB. Prevalence of antimicrobial resistance in intestinal flora of patients undergoing prostatic biopsy: implications for prophylaxis and treatment of infections after biopsy. BJU Int;2010;107(7):1017-20.
Nam RK, Saskin R, Lee Y, Liu Y, Law C, Klotz LH, et al. Increasing hospital admission rates for urological complications after transrectal ultrasound guided prostate biopsy. J Urol 2013;189:S12-S18.
Steensels D, Slabbaert K, De Wever L, Vermeersch P, Van Poppel H, Verhaegen J. Flouroquinoloneresistant E. Coli in intestinal flora of patients undergoing transrectal ultrasound guided prostate biopsy— should we reassess our practices for antibiotic prophylaxis?. Clin Microbiol Infect 2012;18:575-581.
Liss MA, Chang A, Santos R, Nakama-Peeples A, Peterson EM, Osannn K, et al. Prevalence and significance of fluoroquinolone resistant Escherichia coli in patients underogoing transrectal ultrasound guided prostate needle biopsy. J Urol.2001;185(4)1283-8.
Zaytoun OM, Vargo EH, Rajan R, Berglund R, Gordon S, Jones JS. Emergence of fluorquinoloneresistant Escherichia coli as cause of postprostate biopsy infection: Implications for prophylaxis and treatment. Urology 2011; 77 (5): 1035-41