2013, Number 2
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Rev Mex Ing Biomed 2013; 34 (2)
GMM and LDA Applied to Lung Diseases Detection
Mayorga OP, Druzgalski C, Criollo AMA, González AOH
Language: Spanish
References: 25
Page: 131-144
PDF size: 581.37 Kb.
ABSTRACT
This study presents experimentally tested methods, which can be used
for a quantitative assessment of respiratory sounds as the indicators of
pulmonary disorders. In particular, conducted experiments considered
both normal and abnormal lung sounds (LS). As a part of the RALE
Database, signals were recorded from healthy subjects and those with
respiratory disorders. Current medical practices including evaluation of
respiratory diseases often involve qualitative and frequently subjective
auscultation. However, the application of quantitative signal analysis
methods could improve the assessments of these diseases. In particular,
we utilized acoustic evaluation methodologies based on the MFCC (Mel
frequency Cepstral Coefficients) acoustic vectors representation, GMM
(Gaussian Mixed Models), and LDA (Linear Discriminant Analysis). To
assure the validity of determined class models representing diagnostic
classification, the LS signals were cross validated within sequential sets
of respiratory cycles for a given subject as well as cross correlated
within the specific groups of subjects representing particular conditions
of normal or given class of abnormal pulmonary functions. Higher order
MFCC vectors, including 9, 10 and 11 Gaussian mixtures, resulted
in improved classification of the LS attributes, reached up to 98 %
of efficiency recognition. This documented automated classification of
LS makes it suitable for a more efficient mass screening of respiratory
disorders. In particular, the presence of peculiar sounds such as crackles
and wheezes lead to more robust models thus reflecting the useful
applicability of the presented diagnostic tool. These techniques can
assist in broader analysis, identification, and diagnosis of pulmonary
disorders manifested by peculiar auscultatory findings.
REFERENCES
Serra Valdés M A. “Evaluación de la Terapia Inhalada en Pacientes con Asma Bronquial Persistente”.
Hadjileontidais L J. “Biosignal and compression Standards”. M-Health Emerging Mobile Health systems, Topics in Biomedical Engineering’, Springer 2006 International Book Series, 2006; 277-292.
Gross V, Dittmar A, Penzel T, Schutter F, Von Wichert P. “The Relationship between Normal Lung Sounds, Age, and Gender”. Am J Respir Crit Care Med, 2000; 162(905- 909.
Sovijärvi A R A, Vanderschoot J, Earis J E. “Standardization of computerized respiratory sound analysis”. Eur Respir Rev 2000, 2000; 10(77): 585.
Earis J E, Cheetham B M G. “Current methods used for computerize respiratory sound analysis”. Eur Respir Rev 2000, 2000;
Sovijärvi A R A, Malmberg L P, Charbonneau G, Vanderschoot J, Dalmasso F, Sacco C, et al. “Characteristics of breath sounds and adventitious respiratory sounds”. ERS Journals Ltd 2000, 2000; 10(77): 591-596
Bush A. “Diagnosis of asthma in children under five”. Prim Care Respir J, 2007; 16(1): 7-15.
Rossi M, Sovijärvi A R A, Piirilä P, Vannuccini L, Dalmasso F, Vanderschoot J. “Environmental and subject conditions and breathing manoeuvres for respiratory sound recordings”. Eur Respir Rev 2000, 2000; 10(77): 611?615.
Charbonneau G, Ademovic E, Cheetham B, Malmberg L P, Vanderschoot J, Sovijärvi A R A. “Basic techniques for respiratory sound analysis”. Eur Respir Rev 2000, 2000; 10(77): 625-635.
Druzgalski C. “Potentials and Barriers of Extensive Auscultatory Databases”. 27th International Conference on Lung Sounds, 2000; Sweden
Druzgalski C. “Distributed Analysis of Signal Integrity Impediments in Respiratory Acoustic Signatures WC2003”. The World Congress on Medical Physics and Biomedical Engineering, 2003; Sydney, Australia
Druzgalski C, Shenoy N, Kumar S. “Enhanced Pulmonary Function Testing and Segmental Respiratory Performance Evaluation”. The WC on Medical Physics and Biomedical Engineering 2006, 2006; Seoul, Korea
Schreur H J, Vanderschoot J, Zwinderman A H, Dijkman J H, Sterk P J. “Abnormal lung sounds in patients with asthma during episodes with normal lung function”. Chest, 1994; 106(1): 91-9.
Pasterkamp H. “State of Art: Respiratory Sounds Advances beyond the Stethoscope”. Am J Respir Crit Care Med, 1997; 156(3): 974-987.
Martinez W L, Martínez A R. Computational Statistics Handbook With Matlab. Chapman & Hall/CRC 2002.
Pearce D. “An Overview of ETSI Standards Activities for Distributed Speech Recognition Front-Ends”. AVIOS 2000: The Speech Applications Conference, 2000.; San Jose, California, USA
Mayorga P, Besacier L, Lamy R, Serignat J F. “Audio packet loss over IP and speech recognition”. Automatic Speech Recognition and Understanding, 2003. ASRU ’03. 2003 IEEE Workshop on, 2003; St. Thomas, Virgin Islands, USA
Mayorga P, Druzgalski C, Vidales J. “Quantitative Models for Assessment of Respiratory Diseases”. PAHCE 2010, 2010; Lima, Perú
Sahidullah M, Saha G. “Design, analysis and experimental evaluation of block based transformation in MFCC computation for speaker recognition”. Speech Communication, 2012; 54(4): 543-565.
Bahoura M, Pelletier C. “Respiratory sounds classification using cepstral analysis and Gaussian mixture models”. Engineering in Medicine and Biology Society, 2004. IEMBS ’04. 26th Annual International Conference of the IEEE, 2004;
Bahoura M, Pelletier C. “Respiratory sounds classification using Gaussian mixture models”. Electrical and Computer Engineering, 2004. Canadian Conference on, 2004;
Jen-Chien C, Huey-Dong W, Fok-Ching C, Chung I L. “Wheeze Detection Using Cepstral Analysis in Gaussian Mixture Models”. Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE, 2007;
Webb A R. Statistical Pattern Recognition. John Wiley & Sons Ltd, 2002.
Reynolds D A. “A Gaussian Mixture Modeling Approach to Text-Independent speaker Identification”. Georgia Institute of Tecnology, 1992;
Mayorga P, Druzgalski C, Morelos R L, González O H, Vidales J. “Acoustics Based Assessment of Respiratory Diseases using GMM”. EMBC 2010 IEEE, 2010; Buenos Aires, Argentina.