2009, Number 3
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MEDICC Review 2009; 11 (3)
Trends in Cuba’s Cancer incidence (1990 to 2003) and mortality (1990 to 2007)
Galán Y, Fernández L, Torres P, Garcí M
Language: English
References: 58
Page: 19-26
PDF size: 640.05 Kb.
ABSTRACT
Introduction Cancer has been the second cause of death in Cuba since
1958. The National Cancer Registry (NCR) and the National Statistics
Division of the Ministry of Public Health provide incidence, mortality and
other relevant epidemiological data on the disease, as a basis for analysis
and decision-making in public health planning for cancer control.
Objectives Describe trends in incidence and mortality of cancer in
Cuba overall and by sex since 1990, and analyze the most current
3-year data for frequent types and risk of developing and dying from
cancer, by age group, sex, site, and province.
Methods Cancer incidence and mortality were described using ageadjusted rates based on standard world population for 1990–2003 and 1990–2007, respectively. Crude and age-adjusted rates were calculated for the most common sites (excluding nonmelanoma skin cancer) by sex using the latest 3-year incidence data available (2001–
2003) from the National Cancer Registry and mortality data (2005–2007) from the National Statistics Division of the Ministry of Public Health. To compare risk of developing and dying from cancer among Cuban provinces, age-adjusted rates were distributed in quartiles.
Results Cancer incidence and mortality have increased in both sexes
since 1990. In 2001–2003, an average of 23,710 new cancer
cases were diagnosed annually (excluding nonmelanoma skin cancer),
and the average annual risk of developing cancer was 216.5
per 100,000 population for men and 204.0 per 100,000 population
for women. Between 2005 and 2007, there were 19,671 average
annual deaths from cancer in Cuba. The risk of developing and
dying from cancer varies by age group and by geographic location
but was highest in Havana City province. The sites with highest
incidence and mortality were lung, female breast, prostate, colon,
and uterine cervix.
Conclusions Cancer incidence and mortality are increasing in Cuba,
and the differences by site, age, sex and geographical distribution
analyzed in this article, as well as recommended further research,
should serve to inform adoption and implementation of more effective
strategies for the Ministry of Public Health’s national Comprehensive
Cancer Control Program.
REFERENCES
Sener SF, Grey N. The global burden of cancer. J Surg Oncol. 2005 Oct 1;92(1):1–3.
Parkin DM, Bray F, Ferlay J, Pisani P. Global Cancer Statistics, 2002. CA Cancer J Clin. 2005 Mar–Apr;55(2):74–108.
World Health Organization. Plan de Acción propuesto por la OPS para la Prevención y el Control del Cáncer 2008–2015 [monograph on the Internet]. Washington: WHO; 2008 [cited 2008 Dec 22]. Available from: http://www.paho.org/ Spanish/AD/DPC/NC/pcc-proposed-plan.pdf
Kanavos P. The rising burden of cancer in the developing world. Ann Oncol. 2006 Jun;17 Suppl 8:viii15–viii23. Review.
Anuario Estadístico de Salud 2007. [Internet]. Havana: Ministry of Public Health, National Statistics Division; 2008 [cited 2008 Nov 17]. Available from: http://bvs.sld.cu/cgi-bin/wxis/ anuario/?IsisScript=anuario/iah.xis&tag5003=an uario&tag5021=e&tag6000=B&tag5013=GUEST &tag5022=2007
Seuc A, Domínguez E, Galán Y. Esperanza de vida ajustada por cáncer. Rev Cubana Hig Epidemiol [serial on the Internet]. 2003 Apr [cited 2009 Mar 17];41(1). Available from: http://scielo. sld.cu/scielo.php?script=sci_arttext&pid=S1561- 30032003000100004&lng=es&nrm=iso.
Seuc A, Domínguez E, Galán Y. La carga por morbilidad del cáncer. Cuba, año 2000. Rev Cubana Hig Epidemiol [serial on the Internet]. 2006 Aug [cited 2009 Mar 17]; 44(2). Available from: http://scielo.sld.cu/scielo.php?script=sci_ arttext&pid=S1561-30032006000200003&lng=e s&nrm=iso.
Huerta E, Grey N. Cancer Control Opportunities in Low- and Middle-income Countries. CA Cancer J Clin. 2007 Mar–Apr;57(2):72–4.
Pisani P. The Cancer problem in developing countries. In: Tanneberger S, Cavalli F, Pannuti F, editors. Cancer in developing countries. The great challenge for oncology in the 21st Century. Munich: Zuckschwerdt; 2004. p. 21–5.
Ngoma T. World Health Organization cancer priorities in developing countries. Ann Oncology. 2006 Jun;17 Suppl 8:viii9–viii14.
Rodríguez A, Álvarez L. Repercusiones del envejecimiento de la población cubana en el sector salud. Rev Cubana Salud Pública. 2006;32(2):178–82.
Cuba. Oficina Nacional de Estadísticas. Sistema de Información Estadística Nacional de Demografía. Havana: National Statistics Bureau; 2004
Rojas F. Situación, sistema y recursos humanos en salud para el desarrollo en Cuba. Rev Cubana Salud Pública. 2003;29(2):157–69.
Anuario Estadístico de Salud 2000–2007. Havana: Ministry of Public Health, National Statistics Division; 2000–2007. [cited 2008 Nov]. Available from: Available from: http://bvs.sld. cu/cgi-bin/wxis/anuario/?IsisScript=anuario/iah. xis&base=anuario&lang=e
El Envejecimiento de la Población Cubana 2007. Cuba y sus territorios [monograph on the Internet]. Havana: National Statistics Bureau; 2008 [cited 2008 Nov]. Available from: http://www.one. cu/envejecimiento2008.htm.
Cuba: Proyección de la Población. Nivel Nacional y Provincial, Período 2010 – 2030 [monograph on the Internet]. Havana: National Statistics Bureau; [cited 2008 Nov]. Available from: http://www.one.cu/proyecciones%20de%20 la%20poblacion%202010%202030.htm.
Barros O. Escenarios demográficos de la población de Cuba para el próximo milenio [thesis]. Havana: University of Havana; 2000.
Center for Population and Development Studies. El estado actual y perspectivo de la población cubana: Un reto para el desarrollo territorial sostenible [monograph on the Internet]. Havana: National Statistics Bureau. [cited 2008 Dec]. Available from: http://www.one.cu/estadoactual.htm.
Fernández L. Sistema de Información para el Registro Nacional del Cáncer [thesis]. Havana: National Oncoloy and Radiobiology Institute; 1985.
Rodríguez A, Martín AA. El Registro Nacional de Cáncer de Cuba. Procedimientos y resultados. Rev Brasileira de Cancerologia. 2001;47(2):171–7.
Fernández L, Caraballoso M, Rodríguez L. Proposición de un Sistema Automatizado para Procesar la Información del Registro Nacional del Cáncer. Rev Cubana Adm Salud. 1984;10(4):341–6.
Galán Y, Martín A, Rodríguez A, Graupera M, Luaces P, Fernández L. Estimación de la integridad de casos del Registro Nacional de Cáncer de Cuba. Rev Cubana Oncol. 1996;12(1):37–42.
Lage M, Carballoso M, Azcué M. Las posibilidades de reducción de la mortalidad por cáncer en Cuba. Análisis para un Programa Nacional. Rev Cubana Oncol. 1987;3(2):101–30.
Rodríguez A, Martín A, Camacho R. El programa nacional de control de cáncer en Cuba. Rev Brasileira de Cancerologia. 1998;44(2):119–29.
Proyecciones de la salud pública de Cuba para el año 2015 [homepage on the Internet]. Havana: Ministry of Public Health; 2006 [cited 2008 Nov]. Enfermedades no transmisibles y otros daños para la salud. Tumores malignos; [1 screen]. Available from: http://salud2015.sld.cu/factoresrelacionados- con-el-ambiente/plonearticlemultipage. 2006-03-24.5255686058/tumores-malignos.
Martín AA, Galán YH, Rodríguez AJ, Graupera M, Lorenzo Luaces P, Fernández LM, et al. The Cuban National Cancer Registry: 1986–1990. Eur J Epid. 1998 Apr;14(3):287–97.
Doll R, Smith P. Comparison between registries: Age-standardized rates. In: Waterhouse J, Muir CS, Shanmugaratnam S, Powell J, editors. Cancer incidence in five continents. Lyon: IARC; 1982. p. 671–75.
Pan American Health Organization. Clasificación Internacional de Enfermedades para Oncología (CIE-O). 1st ed. Washington: Publicación Científica No. 345;1977.
Boyle P, Anderson B, Andersson L, Ariyaratne Y, Auleley G, Barbacid M, et al. Need for global action for cancer control. Ann Oncol. 2008 Sep;19(9):1519–21.
Ahmad S, O’Mahony MS. Shift in the burden of cancer towards older people—a retrospective population-based study. Int J Clin Pract. 2007 Jun;61(6):931–6.
Allender S, Foster C, Hutchinson L, Arambepola C. Quantification of urbanization in relation to chronic diseases in developing countries: a systematic review. J Urban Health. 2008 Nov;85(6):938–51. Epub 2008 Oct 18.
Lence JJ, Camacho R. Cáncer y transición demográfica en América Latina y el Caribe. Rev Cubana Salud Pública [serial on the Internet]. 2006 Sep [cited 2009 Mar 17];32(3). Available from: http://scielo.sld.cu/scielo.php?script=sci_ arttext&pid=S0864-34662006000300010&lng=e s&nrm=iso.
Center for Population and Development Studies. Panorama Económico y Social. Cuba 2008 [monograph on the Internet]. Havana: National Statistics Bureau; [cited 2008 Nov]. Available from: http://www.one.cu/panoramaeconomico2008.htm.
Barrios E, Galán Y, Sancho-Garnier H, Sabini G, Musé IM. Epidemiología. In: Unión Internacional contra el Cáncer, editor. Prevención del Cáncer. Estrategias basadas en la Evidencia. Una Guía de la UICC para América Latina. UICC; 2006. p. 13–26.
Corrao MA, Guindon GE, Sharma N, Shokoohi DF, editors. Tobacco Control Country Profiles. 1st ed. Atlanta (GA): American Cancer Society; 2000.
Peto R, Darby S, Deo H, Silcocks P, Whitley E, Doll R. Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of national statistics with two casecontrol studies. BMJ. 2000 Aug 5;321(7257):323–9.
Varona P, Herrera D, García R, Romero T, Venero S. Mortalidad atribuible al tabaquismo. Rev Cubana Salud Pública. 2009;35(2):1–13.
González S, Suárez N, Cáceres C, Conde C, Camacho R. Características del hábito de fumar en Cuba. Rev Venezolana de Oncología. 1993;5:93–5.
Bray F, Tyczynski JE, Parkin DM. Going up or coming down? The changing phases of the lung cancer epidemic from 1967 to 1999 in the 15 European Union countries. Eur J Cancer. 2004 Jan;40(1):96–125.
Jha P, Chaloupka FJ, Corrao M, Jacob B. Reducing the burden of smoking world-wide: effectiveness of interventions and their coverage. Drug Alcohol Rev. 2006 Nov;25(6):597–609.
Segunda Encuesta Nacional de Factores de Riesgo de Enfermedades Crónicas no Transmisibles en Cuba. Informe de Trabajo. Havana: National Institute of Hygiene, Epidemiology and Microbiology; 2002.
Shafey O, Dolwick S, Guindon GE, editors. Tobacco Control Country Profiles 2003. 2nd ed. Atlanta: American Cancer Society; 2003.
Bray F, McCarron P, Parkin DM. The changing global patterns of female breast cancer incidence and mortality. Breast Cancer Res. 2004;6(6):229–239. Epub 2004 Aug 26.
Torres P, Guerra M, Galán Y, García M, Lezcano M, Fernández L. Incidencia y mortalidad por cáncer en la mujer cubana. Trienio 2000– 2002. Rev Cubana Med [serial on the Internet]. 2007 Sep [cited 2009 Mar 17];46(2). Available from: http://scielo.sld.cu/scielo.php?script=sci_ arttext&pid=S0034-75232007000200007&lng=e s&nrm=iso.
Torres R, Gran M. Panorama de salud de la mujer cubana. Rev Cubana Salud Pública. 2003;29(3):198–208.
Pan American Health Organization. Evaluación del programa de control del cáncer de cuello de útero en Cuba. Informes Breves. Boletín de la Oficina Panamericana de la Salud. 1996;121(6):577–81.
Rodríguez A, Lence J, Cabezas E, Camacho R. Programa Nacional de Diagnóstico Precoz del Cáncer Cérvicouterino ¿Qué hacer y por qué? Rev Cubana Med General Integral. 1994;10(3):220–4.
Sankaranarayanan R, Budukh A, Rajkumar A. Effective screening programmes for cervical cancer in low- and middle-income developing countries. Bull World Health Organization. 2001;79(10):954–62. Epub 2001 Nov 1.
Clifford GM, Gallus S, Herrero R, Muñoz N, Snijders PJ, Vaccarella S, et al. Worldwide distribution of human papillomavirus types in cytologically normal women in the International Agency for Research on Cancer HPV prevalence surveys: a pooled analysis. Lancet. 2005 Sep 17–23;366(9490):991–8.
Galán Y, Guerra M, Fernández L, Camacho R. Incidence, mortality and survival from prostate cancer in Cuba, 1977–1999. Eur J Cancer Prevention. 2004 Oct;13(5):377–81.
National Oncology Group. Propuesta para abordar el problema Cáncer de Próstata. Unpublished working paper. 2006.
Fernández L, Galán Y, Jiménez R, Gutiérrez A, Guerra M, Pereda C, et al. Estudio de casos y controles sobre factores de riesgo de cáncer de próstata. Rev Cubana Salud Pública. 2005 Jul– Sep;31(3):174–81.
Fernández L, Galán Y, Jiménez R, Gutiérrez A, Guerra M, Pereda C, et al. Sexual behaviour, history of sexually transmitted diseases and the risk of prostate cancer: a case-control study in Cuba. Int J Epidemiol. 2005 Feb;34(1):193–7. Epub 2004 Sep 16.
Caraballoso M. Cuba: National Cancer Registry 1970–1981. In: Parkin DM, Stiller CA, Draper GJ, Bieber CA, editors. International Incidence of Childhood Cancer. Lyon: IARC; 1988. p. 127–30.
Martín A, Valdés A, Longchong M, Grueiro S. Incidencia del cáncer infantil en Cuba (1983– 1987). Rev Cubana Oncol. 1994;10(1–2):50–8.
Parkin DM, Kramárová E, Draper GJ, Masuyer E, Michaelis J, Neglia J, et al, eds. International Incidence of Childhood Cancer, Vol. II. IARC Scientific Publication No. 144. Lyon: IARC; 1998.
Steliarova-Foucher E, Stiller C, Kaatsch P, Berrino F, Coebergh J, Lacour B, et al. Geographical patterns and time trends of cancer incidence and survival among children and adolescents in Europe since the 1970s (the ACCIS project): an epidemiological study. Lancet. 2004;364(9451):2097–105.
Fajardo A, Mejía JM, Hernández L, Mendoza H, Garduño J, Martínez MC. Epidemiología descriptiva de las neoplasias malignas en niños. Rev Panamericana Salud. 1999;6(2):75–88.