2015, Number 3
<< Back Next >>
Rev Cuba Endoc 2015; 26 (3)
Subclinical hypothyroidism in adult women with excessive body weight
Quirantes MAJ, Mesa RBM, Quirantes HAJ
Language: Spanish
References: 12
Page: 246-253
PDF size: 191.92 Kb.
ABSTRACT
Introduction: subclinical hypothyroidism is associated to the increase of body
weight and obesity. The behavior of this illness in adult women, who are seen by a
doctor due to excessive body weight, is unknown.
Objective: to determine the frequency of subclinical hypothyroidism and its
relationship with excessive body weight in adult women under medical control.
Methods: descriptive and cross-sectional study of 45 patients who met the
inclusion criteria and were attended to at the endocrinology service of “Dr. Salvador
Allende” hospital from April to December 2013. The variables were age, weight,
size, body mass index, waist circumference, thyroid-stimulating hormone, T4 and
free T3 thyroid hormones. Median and maximum and minimum values of variables
were determined as well as the association of variables (Pearson's correlation
coefficient).
Results: median was 39 years of age, body mass index of 34.6 kg/m
2, waist
circumference equal to 106 cm, thyroid-stimulating hormone of 1.6 mUI/L, T4= 90 nmol/L and free T3= 3.4 pmol/L; the subclinical hypothyroidism was
11.1%. There was positive correlation of thyroid-stimulating hormone values with the body mass index and the waist circumference (r = 0.378 and r = 0.236,
respectively).
Conclusions: subclinical hypothyroidism was considered high in adult women with body weight excess and the increase of thyroid-stimulating hormone is associated to a rise of body mass index and of waist circumference values in the studied sample.
REFERENCES
Yanovski SZ, Yanovski JA. Obesity. N Engl J Med. 2002;346(8):591-602.
Fontaine KR, Redden DT, Wang C, Westfall AO, Allison DB. Years of life lost due to obesity. JAMA. 2003;289:187-93.
Yanes M. Disfunción tiroidea subclínica. Rev Cubana Endocrinol. 2012;23(3):221-4.
Jiménez S, Rodríguez A, Pita G. Consejería en alimentación y nutrición. Manual de apoyo. La Habana: Instituto de Nutrición e Higiene de los Alimentos. Ministerio de Salud Pública; 2011. p. 62-3.
Frías MC, Tárraga PJ, Rodríguez JA, Solera J, Celada A, López MA, et al. Hipotiroidismo subclínico y factores de riesgo cardiovascular. Nutr Hosp. 2011;26(6):1355-62.
Tunbridge WMG, Evered DC, Hall R. The spectrum of thyroid disorders in a community: The Wickman Survey. Clin Endocrinol (Oxf). 1977;7:481-93.
Wilson George R, Curry Whit JR. Subclinical Thyroid Disease. Am Fam Physician. 2005;72:1517-24.
Lizarzaburu JC, Cornetero V, Núñez V. Hipotiroidismo subclínico y estimación de su frecuencia en síndrome metabólico y obesidad en un grupo poblacional urbano de Lima, Perú. Rev Peru Epidemiol. 2013;17(1):1-5.
Sotolongo O, Rodríguez L. Caracterización clínica del hipotiroidismo en pacientes geriátricos Policlínico Pedro Fonseca. La Lisa, 2011. Rev Habanera de Ciencias Médicas. 2012;11(2):10-6.
Cooper DS. Subclinical hypothyroidism (clinical practice). N Engl J Med. 2001;35(4):260-5.
Marí MC, Toderescu P, Alonso JM, Pérez MI, Sánchez MC, Dumbraveanu A. Hipotiroidismo en tratamiento en el Área de Salud de Guadalajara (España): características y prevalencia estimadas a partir del consumo de hormona tiroidea. Rev Clin Med Fam. 2012;5(2):67-73.
Bonet Gorbea M, Varona Pérez P. III Encuesta Nacional de factores de riesgo y actividades preventivas de enfermedades no transmisibles. Cuba 2010-2011. La Habana: Editorial Ciencias Médicas; 2014. p. 107.