2015, Number 5
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Gac Med Mex 2015; 151 (5)
Heart failure with preserved ejection fraction (HFPEF). Impact of change in the paradigm of isolated diastolic dysfunction
Magaña-Serrano JA, Rosas-Peralta M, Candanosa-Arias C, Valencia-Sánchez S, Garrido-Garduño M, Arriaga-Nava R, Calderón-Abbo MC
Language: Spanish
References: 109
Page: 635-647
PDF size: 792.12 Kb.
ABSTRACT
Heart failure with preserved ejection fraction is a significant and growing public health problem, since it currently represents
half of all patients with heart failure. Despite improvements in the understanding of the disease, there is no benefit form
treatments tested at all. Advances in diagnostic imaging and invasive evaluation algorithms will allow a more accurate and
early diagnosis so that treatment of earliest forms in the progression of the disease are applied since the potential for benefit
may be higher. Although important progress has been made in our understanding of the pathophysiology, cardiac catheterization,
and cellular of diastolic failure mechanisms and not diastolic mechanisms of disease, further research is required promptly
to determine how best to address these anomalies to reduce the significant burden of morbidity and mortality in this form of
heart failure, which is reaching pandemic proportions.
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