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2015, Number 3

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Residente 2015; 10 (3)

Interleucina-18 en síndrome metabólico

Dávalos-de la Cruz AP, Flores-Chávez A, Hernández-Cuervo P, Ramírez-Villafańa M, González-Ponce F, Bonilla-Lara D, Contreras-Moreno MG, Trujillo-Hernández B, Gámez-Nava JI

Language: Spanish
References: 36
Page: 118-124
PDF size: 226.15 Kb.


ABSTRACT

Metabolic syndrome (MS) is an entity that occurs with a frequency of 41.6% in Mexico, it is associated with a state of chronic inflammation in wich multiple cytokines are involved. This review article describes the current scientific evidence that suggests that interleukin-18 (IL-18) could be closely related to the MS and its consequences. There has been observed an increase in serum levels of IL-18 MS and detected expression of IL-18 in the unstable atherosclerotic plaque in adipose tissue and muscle tissue. This article also discusses the pathogenic aspects in which IL-18 could play a role in the development of MS.


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