2015, Number 11
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Ginecol Obstet Mex 2015; 83 (11)
Impact of laser-assisted hatching Aceptado: septiembre 2015 (quarter technique) in poor prognosis patients
González-Ortega C, Cancino-Villarreal P, Anaya-Torres FJ, Pérez-Peña E, Gutiérrez-Gutiérrez AM
Language: Spanish
References: 41
Page: 670-679
PDF size: 393.53 Kb.
ABSTRACT
Background: Poor implantation rates continue to be the determinant
factor for results in assisted reproductive techniques; many factors are
thought to be involved including embryo quality, endometrial receptivity
and embryo transfer. Assisted hatching has been proposed as a
technique to improve implantation rates in selected groups of patients,
especially with poor prognosis
Objective: To evaluate the impact of the laser assisted hatching performed
with quarter technique in patients with poor prognosis.
Material and methods: Prospective, controlled and randomized clinical
study. The study group included patients with poor prognosis: maternal
age ≥ 38 years, basal FSH ≥ 12.0 mUI/mL, two or more previous FIV/
ICSI failures. The control group don´t received neither assisted reproductive
techniques.
Results: We registered 303 cycles: n=154 in study group (laser assisted
hatching) and n=149 in control group. Clinical pregnancy (40.1
vs
19.7%) and implantation (17.5
vs 8.3%) rates were significant higher
in laser assisted hatching group, there were not significant differences
between multiple pregnancy (13.11
vs 10%) and miscarriage (14.7
vs
17.2) rates.
Conclusion: Laser assisted hatching with quarter technique improves
pregnancy and implantation rates in poor prognosis patients
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