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2015, Number 2

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Med Cutan Iber Lat Am 2015; 43 (2)

Sarcoidosis: apropos of a case with extensive skin involvement

Pinto QSMV, Filho FB, Monteiro CCG, Coelho MP, Ribeiro SC, Regazzi AJC

Language: Portugués
References: 10
Page: 142-144
PDF size: 399.12 Kb.


ABSTRACT

Sarcoidosis is a granulomatous disease of unknown etiology whose cutaneous manifestations may be the first sign of the disease. Due to the polymorphism of the cutaneous lesions, it is known for mimicking other diseases, thus, representing an important diagnostic challenge. Histopathologically, it is characterized by epithelioid, noncaseating granulomas. In our case, there was only an extensive cutaneous manifestation, without involvement of other organs, with a characteristic histopathology. The choice of treatment with hydroxychloroquine was based on the extent of the lesions and the cosmetic appearance of the patient.


REFERENCES

  1. Bolognia JL, Jorizzo JL, Rapini RP. Granulomas não infecciosos. Dermatologia. 2a ed. Rio de Janeiro: Elsevier; 2008. pp. 1421-1426.

  2. Daldon PEC, Arruda LHF. Granulomas não-infecciosos: Sarcoidose. Anais Bras Dermato. 2007; 82: 559-571.

  3. Fernández-Faith E, McDonnell J. Cutaneous sarcoidosis: differential diagnosis. Clin Dermatol. 2007; 25: 276-287.

  4. Mana JMD, Marcoval J, Graells J, Salazar A, Peyrí J, Pujol R. Cutaneous involvement in sarcoidosis. Arch Dermatol. 1997; 133: 882-887.

  5. Hunninchake GW, Costabel U, Ando M. Statement on sarcoidosis. Am J Resp Crit Care Med. 1999; 160: 736-755.

  6. Azulay RD, Azulay DR, Azulay-Abulafia L. Distúrbois relacionados com as células de Langerhans e os macrófagos. Sarcoidose. En: Azulay RD, Azulay DR, Azulay-Abulafia L. Dermatologia. 6a ed. Río de Janeiro: Guanabara Koogan; 2013.

  7. Haimovic A, Sánchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist: Part I. Cutaneous disease. J Am Acad Dermatol. 2012; 66: 699.

  8. Veien NK, Stahl D, Brodthagen H. Cutaneous sarcoidosis in Caucasians. J Am Acad Dermatol. 1987; 16 (3 pt 1): 534-540.

  9. Chen ES, Moller DR. Sarcoidosis, scientific progress and clinical challenges. Nat Rev Rheumatol. 2011; 7: 457-467.

  10. Zic JA, Horowitz DH, Arzubiaga C, King LE Jr. Treatment of cutaneous sarcoidosis with chloroquine. Review of the literature. Arch Dermatol. 1991; 127: 1034-1040.




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