Cortés-Ramírez JM, Cortés-de la Torre JMJ, Cortés-de la Torre RA, Salazar-de Santiago A, Salazar-Fernández LO, Ramírez-Rodríguez M, de la Torre-Murillo R, Carlos-de la Torre MJ, Castelo-Ramos OO

Language: Spanish
References: 5
Page: 622-625
PDF size: 389.31 Kb.

ABSTRACT

Hereditary ichthyosis affects skin keratinization or cornification; It manifested by dry, scaly, thick, hyperpigmented skin, fragile and sometimes blistering, which appears to touch her. "Tightness" of the eyelids and lips; problems with hair growth and psychomotor disturbances. It appears in acuchildhood and remains for life, with mild disease. Signs and symptoms usually disappear during the summer, although there are severe forms. Acquired ichthyosis related to other diseases manifest at any age, either as a systemic disease or paraneoplastic syndrome. Hypothyroid patients suffering from skin disorders: diffuse hyperpigmentation, skin dry and coarse, and chronic urticaria. Generalized myxedema is the most common feature. Demonstrations associated include: weight gain, lethargy, weakness, loss of appetite, intolerance to cold, cold, pale and dry skin.
Clinical case: 50 year old with congenital pulmonary stenosis. In June 2014 he referred drowsiness, fatigue, generalized edema, weight gain and weakness. Physical examination: blood pressure 90/60 mmHg, weight 76 kg, heart rate of 55 per minute; dry, hyperpigmented, thick, scaly, conaumento volume of thyroid lobes, skin RS RS CS expulsion lung, generalized hyporeflexia. Laboratory studies: 392.9 total cholesterol, triglycerides 346.7, T 3 Total 0.30 0.40 Free T3, T4 Total 10.7 free T4 1.01. HST over l00. The ultrasound showed changes thyroiditis goiter. The histopathological study reported: hyperkeratosis with reduced or absent, discrete to moderate surface hyperkeratosis, in partnership with a thin layer grained, grainy even absent; follicular involvement without inflammatory response. Treatment was initiated with levothyroxine. In March 2015 the symptoms disappeared; blood pressure of 110/70 mmHg, weight 73 kg, heart rate of 75 identified, and disappeared ichthyosis. Laboratory studies reported: T3 and total and free T4 within normal parameters; TSH only remained high (8.30).

REFERENCES

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