2015, Number 2
<< Back
Rev Cubana Plant Med 2015; 20 (2)
Dry and milled vegetable material from Acrocomia crispa fruits to be used in D005 production
Sierra PRC, González CVL, Vicente MR, Morales RCL, Rodríguez LEA, Marrero DD
Language: Spanish
References: 13
Page: 246-252
PDF size: 335.43 Kb.
ABSTRACT
D005, a new antiinfamatory active ingredient, is obtained from ripe fruits of
Acrocomia crispa (Kunth C.F. Baker ex. Becc. Since there are no previous experiences on the processing of these fruits, neither on the physicochemical characteristics or composition
of the vegetable material used for obtaining D005.
To establish the methods for drying and milling these fruits, and to characterize the vegetable material obtained. For determining the more useful method for processing the fruits, samples of fresh fruits were dried at 60 °C and at room temperature, and samples of dry fruits were milled using ball and hammer mills.
It was established the drying at room temperature at shadow for 25 days and the use of a hammer mill with mesh opening of 2.36 mm. Eight batches, processed as
previously stated, were characterized taking into account residual humidity (‹ 8 %), ash content (total: 2.30-3.87 %; acid insoluble: 0.70-0.97 %; water soluble:
0.44-1.59 %), oil content (13-18 %), and fatty acid content (total: 92-96 % and free: 1-3 %) in the oil. It was established the method for processing the ripe fruits of
A. crispa and it was preliminary characterized the obtained dry and milled vegetable material.
REFERENCES
Miranda M, Cuellar A. Farmacognosia y Productos Naturales. La Habana: Félix Varela; 2001.
Miranda M, Cuellar A, Pérez MB. Manual de prácticas de laboratorio de análisis farmacognóstico. La Habana: Instituto de Farmacia y Alimentos de la UH;1992.
Ministerio de Salud Pública. NRSP No. 309. Medicamentos de origen vegetal: droga cruda. Métodos de ensayos. La Habana: MINSAP;1992.
WHO (1998). Quality Control Methods for Medicinal Plant Materials. Geneva: World Health Organization; 1998.
The United Stated Pharmacopoeia 33 and National Formulary 28 [CD-ROM]. USA: The United States Pharmacopeial Convention, Inc;2010.
González VL, Sierra R, Mas R, Pérez Y, Oyarzábal A, Rodríguez E, et al. Compounds from the fruits of Acrocomia crispa andAcrocomia aculeata for use against oxidative stress and inflammation. Patente wo2013189467. citado jun 2014. Disponible en: http://www.google.com/patents/WO2013189467A2?cl=es
Rodríguez EA, González V, Marrero D, Sgambelluri AR, Adames Y. Fatty acid composition and oil yield in fruits of five Arecaceae species grown in Cuba. J. Am. Oil. Chem. Soc. 2007;84:765-7.
Wan P, Dowd M, Thomas A, Butler B. Trimethylsilyl derivatization / Gas Chromatography as a method to determine the free fatty acid content of vegetable oils. J. Am. Oil. Chem. Soc. 2007;84:701-8.
Dransfield J, Uhl NW, Asmussen CB, Baker WJ, Harley MM, Lewis CE, et al. Genera Palmarum – the evolution and classification of palms. Kew: Royal Botanic Gardens; 2008.
Rodríguez E, González V, Adames Y. Caracterización del material vegetal empleado en la obtención del ingrediente activo D-004. Rev Cubana Plant Med. 2007;12(3):1-3.
Rodríguez EA, González VL, Marrero D, Leiva AT, Vicente R. Fracciones lipídicas obtenidas a partir de frutos de Serenoa repens recolectados en Cuba. Rev Cubana Plant Med. 2012;17(1):11-20.
Basiron Y, Chan KW. The oil palm and its sustainability. J Oil Palm Res. 2004;16:1-10.
Rodríguez EA, Sierra R, González VL, Marrero D, Vicente R. Aceite de Roystonea regia: estudios preliminares. Rev CENIC Ciencias Químicas. 2010;41 (No. Especial).