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ISSN 1817-5996 (Electronic)

2015, Number 3

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Rev Cub de Reu 2015; 17 (3)

Neurobehçet

García-Rivero AA, Gonzalez-Argote J, Martínez LJP

Language: Spanish
References: 40
Page: 222-233
PDF size: 224.99 Kb.


ABSTRACT

Introduction: Behcet's disease is a multisystem inflammatory disorder of unknown etiology characterized by oral, genital ulcers and uveitis.
Objective: To describe the neurological manifestations in Behcet's disease.
Development: the neurological manifestations are divided intra-axial and extra-axial. The most common forms of presentation are the pyramidal disorders, signs of brainstem involvement and cognitive and/or behavioral disorders. Differential diagnoses are multiple sclerosis, cerebrovascular disease adult, meningitis and other neurological diseases. It is vital for accurate diagnosis means the use of neuroimaging, which demonstrate the correlation between symptoms and radiological findings. The concentration of IL-6 in cerebral spinal fluid is correlated with disease activity. Theoretically, any drug used for treatment of Behcet's disease, may be administered in the neurobehçet. But the pathophysiological differences and prognosis of this syndrome need a selection and adjustment of immunosuppressive therapy.
Conclusions: it was a challenge for modern medicine finding common features for the study of neurological manifestations of Behcet's disease.


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