2015, Number 3
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Rev Cub de Reu 2015; 17 (3)
Traditional risk factors and non traditional in a population of rheumatoid arthritis patients
Batún GJAJ, Hernández NÉ, Olán F
Language: Spanish
References: 30
Page: 200-207
PDF size: 145.58 Kb.
ABSTRACT
Introduction: patients with rheumatoid arthritis have twice the risk of cardiovascular diseases. This risk is not explained only by nontraditional factors, because these patients have associated factors with the disease itself which produce chronic inflammation.
Objective: determine the prevalence of traditional cardiovascular risk factors and non-traditional in a population of patients with rheumatoid arthritis.
Methods: a descriptive, cross-sectional, observational and prospective study was done in 126 patients diagnosed with rheumatoid arthritis according to ACR / EULAR 2010 criteria. Medical records were reviewed, excluding patients with previous cardiovascular disease. Traditional cardiovascular risk factors were recorded diabetes mellitus, hypertension, hypothyroidism, smoking, obesity, total cholesterol, HDL and LDL, triglycerides, and factors associated with rheumatoid arthritis, disease duration were recorded, DAS-28 C reactive protein, C reactive protein levels, use of glucocorticoids, rheumatoid factor positive, and positive antibody anti cyclic citrullinated peptide.
Results: 68 % of the population had hypertriglyceridemia, 60.3 % elevated LDL, 50 % hypercholesterolemia, 44.3 % hypoalphalipoproteinemia, 58.7 % presented obesity, 35.7 % had diabetes mellitus, 16.6 % hypertension , 7.1 % smoked and 3.1 % had hypothyroidism. Regarding the non-traditional risk factors 68.2 % had positive rheumatoid factor, 54.7 % were taking glucocorticoids, 25.4 % had C reactive protein › 2 mg / L, 20.6 % had more than 10 years of duration of the illness, the 7.9 % had positive antibody anti cyclic citrullinated peptide and 1.6 % had severe activity index. cardiovascular risk factors 10 years was calculated using the Framingham; 74.6 % showed slight risk, 24.6 % moderate and 0.8 % severe.
Conclusions: our rheumatoid arthritis patients had approximately two average nontraditional cardiovascular risk factors, which makes risk factors such as the Framingham not useful.
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