2015, Number 3
<< Back Next >>
Rev cubana med 2015; 54 (3)
Menopause and hypertension: from biology to clinical practice
Navarro DDA
Language: Spanish
References: 40
Page: 239-251
PDF size: 274.42 Kb.
ABSTRACT
Cardiovascular disease is the leading cause of morbidity and mortality in women
over 50 years, which coincides with natural menopause and that gives connotation
as a health problem and socioeconomic importance to this physiological
phenomenon. Blood pressure levels, after menopause, tend to increase in women
compared to men of the same age. The prevalence of hypertension is similar for
men and postmenopausal women. These epidemiological elements linked to basic
studies conferred to estrogen an important role in controlling blood pressure in
women. For over 40 years, deaths from cardiovascular disease gradually decline in
men, not in women. Ambulatory blood pressure monitoring showed a common
pattern in women with no dipper future cardiac complications and less tendency to
control blood pressure, however, no difference in usual therapeutic measures for
monitoring hypertension are among men and women. Taking into account the
important role of middle-aged women in Cuban society, we proposed: 1. identify
the peculiarities of hypertension in Cuban women in general and particularly in
middle aged women; 2. update the physiological bases related to the influence of
sex steroids and other biological and social factors on vascular physiology, and 3.
consider need to prescribe specific therapeutic measures for hypertension control in
menopause stage women. At least in our environment no characteristics of
hypertension are observed in women during middle age, although there is a guide
for diagnosis and treatment referring to menopause as a potential event of vascular
risk, it does not propose different treatment according to sex.
REFERENCES
Tagle R, Acevedo M. HiperTA en la mujer adulta. Rev Med Chile. 2013;141:237-47.
Reckelhoff J. Gender differences in the regulation of blood pressure. Hypertension. 2001;37:1199-208.
Maranon R, Reckelhoff J. Sex and gender differences in control of blood pressure. Clin Sci (Lond). 2013;125(7):311-8.
Taddei S. Blood pressure through aging and menopause. Climacteric. 2009;12(Suppl 1):36-40.
Cutler JA, Sorlie PD, Wolz M, Thom T, Fields LE, Roccella EJ. Trends in hypertension prevalence: awareness, treatment, and control rates in United States adults between 1988-1994 and 1999-2004. Hypertension. 2008:52:818-27.
Piper MA, Evans CV, Burda BU, Margolis KL, O Connor E, Smith N, et al. Screening for high blood pressure in adults; A systematic evidence review for the U.S. preventive services task force evidence synthesis. No. 12. AHRQ Publication No. 13-05194-EF-1. Rockville, MD: Agency for healthcare Research and Quality; 2014.
República de Cuba. Anuario estadístico de Salud 2013. [citado 14 may 2015]. Disponible en: http://files.sld.cu/dne/files/2014/05/anuario-2013-esp-e.pdf
Navarro D. Consecuencia hormonal del cese de la función reproductiva del ovario. Cap. 2. En: Artiles L, Manzano BR, Navarro D, editores. Climaterio y menopausia un enfoque desde lo social. La Habana: Editorial Científico Técnica; 2008.
Navarro D. HiperTA y menopausia. En: L Artilles, B, Manzano, D. Navarro, editores. Climaterio y Menopausia un enfoque desde lo social. La Habana: Editorial Científico Técnica; 2008. p. 302-12.
Bonet M, Varona P. Hipertensión arterial. En: III Encuesta Nacional de factores de riesgo y actividades preventiva de enfermedades no trasmisibles. Cuba, 2010- 2011. La Habana: ECIMED; 2014. p. 136-6.
República de Cuba. Anuario estadístico de Salud 2014. [citado 14 may 2015]. Disponible en: http://files.sld.cu/dne/files/2014/05/anuario-2013-esp-e.pdf
Heredia Hernández B, Lugones Botell M. Entorno familiar, laboral, manifestaciones clínicas y enfermedades crónicas en mujeres de edad mediana. Rev Cubana Med Gen Integr [revista en la Internet]. 2009 Sep [citado 14 may 2015];25(2). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864- 21252009000200008&lng=es
Lugones Botell M, Valdés Domínguez S, Pérez Piñero J. Caracterización de la mujer en la etapa del climaterio. Rev Cubana Obstet Ginecol [revista en la Internet]. Abr 2001 [citado 14 may 2015];27(1):22-27. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138- 600X2001000100004&lng=es
Fernández Milán AM, Navarro Despaigne D. Adiposidad total, su distribución abdominal. Rev Cubana Obstet Ginecol. 2010;36(3):433-9.
Navarro Despaigne D, Padrón Durán RS, Seuc Jo A, Desdin Silva M. Factores relacionados con las características del síndrome climatérico en un grupo de mujeres cubanas. Rev Cubana Endocr. 1999;10(2):116-23.
Navarro D, Fontaine Y. Síndrome climatérico: su repercusión en mujeres de edad mediana. Rev Cubana Med Gen Integr [serie en internet]. 2001 [citado 15 may 2015];];17(2). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864- 21252001000200010&lng=es&nrm=iso
Zambrana RE, Lopez L, Dinwiddie GY, Ray R, Phillips LS, Trevisan M, et al. Prevalence and incident prehypertension and hypertension in postmenopausal hispanic women: results from the Womens health initiative. Am J Hypertension. 2014:27(3);372-81.
Sjöberg L, Kaaja R, Tuomilehto J. Epidemiology of postmenopausal hypertension. Int J Clin Pract. Suppl 2001;139:4-12.
Casiglia E, Tikhonoff V, Caffi S, Bascelli A, Schiavon L, Guidotti F, et al. Menopause does not affect blood pressure and risk profile, and menopausal women do not become similar to men. J Hypertens. 2008;26(10):1983-92.
Ojeda NB, Intapad S, Alexander BT. Sex differences in the developmental programming of hypertension. Acta Physiol (Oxf). 2014;210(2):307-16.
Hart ECJ, Charkoudian N. Sympathetic neural regulation of blood pressure: influences of sex and aging. Physiology. 2014;29:8-15.
Bojar I, Gujski M, Rackzkiewcz D, Owoc J, Walecka I. Estradiolk level and occurrence of atherosclerosis risk factors in healkthy post menopausal women. Med Sci Monit. 2015:21;970-9.
Maric-Bilkan C, Gilber EM, Ryan J. Impact of ovarian function on cardiovascular health in women: focus on hypertension. Int J Women’s Health. 2014;6:131-9.
Maturana MA, Irigoyen MC, Spritzer PM. Menopause, estrogens, and endothelial dysfunction: current concepts. Clinics. 2007;62(1):77-86.
Meadows JL, Vaughan DE. Endothelial biology in the post menopausal obese women. Maturitas. 2011;69(2):120-5. Doi: 10.1016j.maturitas. 2011.03.012.
Wassertheil-Smoller S, Anderson G, Psaty B, Black H, Manson J, Wong N, et al. Hypertension and its treatment in postmenopausal women . Baseline data from the Womens health Initiative. Hypertension. 2000;36:780-9.
Kim J, Kim T, Lee H, Lee S, Wang T. Postmenopausal hypertension and sodium sensitivity. J Menopausal Med. 2014;20:1-6.
Navarro D, Nicolau O. Terapia hormonal y calidad del hueso. Rev Cubana Endocrinol [revista en la Internet]. 2005 [citado 9 mar 2015];16(2). Disponible en: http://www.bvs.sld.cu/revistas/end/vol16_2_05/end03205.htm
Cannoletta M, Cagnacci A. Modification of blood pressure in postmenopausal women: role of hormone replacement therapy. Int J Women’s Health. 2014;6:745-57.
García I, Navarro D. Influencia del entorno familiar en la mujer en etapa. Rev Cubana Med Gen Integr. 2011;27(2):143-54.
Artiles VL. Incorporating a Gender Perspective into Cuba’s Health System: Realities and Challenges. Medicc Review. 2012 [citado 9 mar 2015];14(2). Disponible en: http://www.medicc.org/mediccreview/articles/mr253.pdf
Sariol Y, Navarro D. Etapas del climaterio y función endotelial en mujeres de edad mediana. Rev Cubana Endocrinol. 2015;26(2):138-46.
Varenna M, Manara M, Galli L, Binelli L, Zucchi F, Sinigaglia L. The association between osteoporosis and hypertension: the role of a low dairy intake. Calcif Tissue Int. 2013 Jul;93(1):86-92.
Chan Q, Stamler J, Elliot P. Dietary factors and higher blood pressure in africanamericans. Curr Hypertens Rep. 201;17;DOI 1007/s11906-014-0517-x
Routledge FS, McFetridge-Durdle JA, Dean CR. Night-time blood pressure patterns and target organ damage: A review. Can J Cardiol. 2007;23(2):132-8.
Yang SG, Mlcek M, Kittnar O. Estrogen Can Modulate Menopausal Women’s Heart Rate Variability. Physiol Res. 2013;62(Suppl. 1):S165-S171.
Mahabala Ch, Kamath P, Bhaskaran U, Pai N, Pai AO. Antihypertensive therapy: nocturnal dippers and nondippers. Do we treat them differently? Vascular Health and Risk Management. 2012;9:123-33.
Burnier M, Viugnier Y, Wuerzner G. State of the art treatment of hypertension: established and new drugs. European J. 2014;35:557-62.
Comisión Nacional Técnica Asesora del Programa de Hipertensión Arterial. Hipertensión arterial. Guía para la prevención, diagnóstico y tratamiento. La Habana: ECIMED; 2008.
Gerdts E, Okin PM, de Simone G, Cramariuc D, Wachtell K, Boman K, et al. Gender differences in left ventricular structure and function during antihypertensive treatment: the Losartan Intervention for Endpoint Reduction in Hypertension Study. Hypertension. 2008 Apr;51(4):1109-14.