2005, Number 6
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Acta Pediatr Mex 2005; 26 (6)
Sevovluorane as a cause of seizures. Report of a case
Pérez HA, Mancera EG
Language: Spanish
References: 10
Page: 299-301
PDF size: 34.38 Kb.
ABSTRACT
Inhalatory induction of anesthesia by face mask is a common practice in children and very useful in outpatient surgery. With this method, children breath inhalant anesthetics through a face mask until loss of consciousness is accomplished, whence a venous line is placed whithout causing anxiety or pain to the patient. Sevofluorane is the volatile agent of choice in anesthesia for children due to its properties which include fast tissue uptake, fast elimination, lack of respiratory irritation, fast adjusment of anesthethic depth and cardiovascular stability. We present the case of a 13 year-old boy who underwent an endoscopic gastrointestinal procedure under general anesthesia with face mask induction; during the procedure the patient developed seizures caused by inhalation of sevofluorane, which could not be controlled with the intravenous administration of 3 mg of midazolam. Heart rate, blood pressure, and oxygen saturation remained stable during the seizures; no neurological abnormalities were observed and the patient remained stable thereafter. He was discharged in good condition.
REFERENCES
Adachi M, Ikemoto Y, Takima C. Seizure-like movements during induction of anaesthesia with sevofluorane. Br J Anaesth 1992;68:214-5
Lerman J. Inhalational agents. En: Bissonnette B. Pediatric Anaesthesia. McGraw-Hill 200;pp215-7
Kaike K, Satu K, Rine J, et al. Epilleptiform discharges during 2 MAC sevofluorane anaesthesia in two healthy volunteers. Anesthesiology 1999;91:1952-5
Cheryl AH, Drummond JC. Seizure-like activity on emergence from sevoflurane anesthesia. Anesthesiology 2000;93:1357-9
Komatsu H, Taie S, Endo S, et al. Electrical seizures during sevofluorane anesthesia in two pediatric patients with epilepsy. Anesthesiology 1994;81:1535-7
Kankala AY, Vakkuri A, Sarkela M, et al. Epileptiform electroencephalogram during mask induction of anesthesia with sevofluorane. Anesthesiology 1999;91:1596-603
Takehiko I, Nakamura Z, Iwao Y, et al. The epileptogenic properties of the volatile anesthetics sevofluorane and isofluorane in patients with epilepsy. Anesthesia-Analgesia 2000;91:989-95
Woodforth IJ, Kicks RG, Crawford MR, et al. Electroencephalographic evidence of seizure activity under deep sevofluorane anesthesia in a nonepileptic patient. Anesthesiology 1997;87:1579-82
Serrano-Pozo A, López-Muñoz MM, Franco-Macías E, et al. Crisis generalizada tonicoclónica provocada por anestesia con propofol y sevofluorano. Rev Neurol 2004;39:693-4
Constant I, Seeman R, Murat I. Sevofluorane and epileptiform EEG changes. Pediatr Anesth 2005;15:266-74