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2015, Number 3

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Dermatología Cosmética, Médica y Quirúrgica 2015; 13 (3)

Field Cancerization, Actinic Keratosis and Squamous Cell Carcinoma: A Model of Progression Documented by Dermoscopy and Reflectance Confocal Microscopy

Roldán MR, Carlos OB

Language: Spanish
References: 31
Page: 240-245
PDF size: 369.47 Kb.


ABSTRACT

Ultraviolet radiation is the most common environmental carcinogen for human beings. Actinic keratosis are an intraepidermal proliferation of atypical keratinocytes which may potentially evolve into squamous cell carcinoma. Actinic keratosis result from excessive chronic sun exposure. The relative risk of progression for actinic keratosis into squamous cell carcinoma depends mainly on the total number of lesions and the immune status of the patient. Field cancerization refers to the presence of multiple subclinical actinic keratosis adjacent to a visible lesion. Dermoscopy and reflectance confocal microscopy are noninvasive diagnostic tools which allow a better recognition and therapeutic approach to actinic keratosis and field cancerization.


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