Gutiérrez-Aguirre CH, de la Garza-Salazar F, Guerrero-González G, Ibarra-Santibáñez SG, García-Mata AS, Cadenas-Justo CI, Gómez-Almaguer D

Language: Spanish
References: 13
Page: 217-223
PDF size: 435.72 Kb.

ABSTRACT

Background: Allogeneic peripheral blood stem cell transplant is used as treatment for hematologic malignancies. It is not frequent that donors present side effects; however, anxiety is a condition that donors may be experimenting since being evaluated as a suitable donor.
Objective: To investigate the anxiety level in peripheral blood stem cell donors.
Material and method: A prospective, longitudinal, observational and descriptive study in which allogeneic peripheral blood stem cell donors were included. A survey-type study was included using the Stait Trait and Anxiety Inventory (STAI) in order to determine anxiety level in donors at the beginning of cell mobilization, before cell harvesting and 24-hour after collection. Anxiety level was classified into mild, moderate and high.
Results: Fifteen cell donors were included, 6 males and 9 females, within an average age of 39.8 years old. Anxiety level was higher in the first survey since moderate anxiety was present in 40% of patients, meanwhile in surveys 2 and 3, 93% and 100% of patients presented mild anxiety levels, respectively. There was a negative correlation between age and anxiety condition (older patient had less anxiety), positive correlation between anxiety condition with female gender (females was correlated with higher levels of anxiety), and with the number of children (to more children higher anxiety level).
Conclusion: Peripheral blood stem cell donors have higher anxiety levels before the donation process, which can be explained by fear to unknown, to the side-effects of filgrastim or to undergo an invasive procedure.

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