2015, Number 2
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Investigación en Discapacidad 2015; 4 (2)
Determination of frequency in primary open angle glaucoma in patients over 40 years in a third-level healthcare centre in Mexico City
Gálvez-Rosas A, Serrano-Miranda AT, Mundo-Fernández EE, Domínguez-Dueñas F, Barojas-Weber E
Language: Spanish
References: 28
Page: 65-70
PDF size: 156.72 Kb.
ABSTRACT
Purpose: To determine the frequency of primary open-angle glaucoma in adults in the Instituto Nacional de Rehabilitación, México, D.F.
Methods: A transverse and retrospective trial by revision of the records of 1,020 patients with glaucoma from the Ophthalmology Department at the Instituto Nacional de Rehabilitación (INR) by the cross-sectional procedure. All patients over 40 years who had been diagnosed with primary open-angle glaucoma (POAG) were selected at the outpatient care dept. Information was obtained through the automated hospital information system (AHIS). Obtained data were: visual acuity, intraocular pressure of both eyes, biomicroscopy, gonioscopy, fundoscopy and the diagnostic of glaucoma. Data base was processed by SPSS V
20.
Results: Out of the 1,020 individuals examined, there were 341 men (33.4 %) and 679 women (66.6 %). The mean age of patients was 70.67 ± 11.16 years (range, 40 to 98). Rate of population from Mexico City was 69.7%. Patients clinically diagnosed of POAG were 548 (53.7%), followed by glaucoma suspect (26.2 %), primary closed angle glaucoma (6.5%), neovascular glaucoma and pseudoexfoliative glaucoma were 3.9 and 3.6% respectively. Other glaucomas were 4.5%. The frequency of POAG in this study was 2.55%.
Conclusions: These results display the need of carrying out multicenter studies of POAG to establish with certainty the regional and national prevalence; as well as designing preventive strategies for early diagnosis and to increase health care coverage to this health problem.
REFERENCES
Fan BJ, Wiggs JL. Glaucoma: genes, phenotypes, and new directions for therapy. J Clin Invest. 2010; 120 (9): 3064-3072.
Pan Y, Varma R. Natural history of glaucoma. Indian J Ophthalmol. 2011; 59 (Suppl 1): S19-23.
Quigley HA. Glaucoma. Lancet. 2011; 377 (9774): 1367-1377.
Sharts-Hopko NC, Glynn-Milley C. Primary open-angle glaucoma; Catching and treating the sneak thief of sight. Am J Nurs. 2009; 109 (2): 40-47.
Rao KN, Nagireddy S, Chakrabarti S. Complex genetic mechanisms in glaucoma: an overview. Indian J Ophthalmol. 2011; 59 (Suppl): S31-S42.
Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006; 90: 262-267.
Challa P. Genetics of adult glaucoma. Int Opthamol Clin. 2011; 51 (3): 37-51.
Coleman AL, Miglior S. Risk factors for glaucoma onset and progression. Surv Ophthalmol. 2008; 53 (Suppl 1): S3-S10.
Kong X, Zhu W, Chen X et al. Familial aggregation of primary open angle glaucoma in Shanghai, China. Mol Vis. 2013; 19: 1859-1865.
Miglior S, Zeyen T, Pfeiffer N et al. Results of the European glaucoma prevention study. Ophthalmology. 2005; 112: 366-375.
Kooner KS, Albdoor M, Cho BJ et al. Risk factors for progression to blindness in high tension primary open angle glaucoma: Comparison of blind and nonblind subjects. Clin Ophthalmol. 2008; 2 (4): 757-762.
Yanagi M, Kawasaki R, Wang JJ et al. Vascular risk factors in glaucoma: a review. Clin Experiment Ophthalmol. 2011; 39: 252-258.
Klein BE, Klein R, Ritter LL. Relationship of drinking alcohol and smoking to prevalence of open-angle glaucoma. The Beaver Dam Eye Study. Ophthalmology. 1993; 100: 1609-1613.
Cheng AC, Pang CP, Leung AT. The association between cigarette smoking and ocular diseases. Hong Kong Med J. 2000; 6 (2): 195-202.
Tielsh JM, Sommer A, Katz J, Royall RM, Quigley HA, Javitt J. Racial variation in the prevalence of primary open-angle glaucoma. The Baltimore Eye Survey. JAMA. 1991; 266 (3): 369-374.
Le A, Mukesh BN, McCarty CA et al. Risk factors associated with the incidence of open-angle glaucoma: the visual impairment Project. Invest Ophthalmol Vis Sci. 2003; 44: 3783-3789.
Kahn HA, Milton RC. Alternative definitions of open-angle glaucoma. Effect on prevalence and associations in the Framingham eye study. Arch Ophthalmol. 1980; 98: 2172-2177.
Schoff EO, Hattenhauer MG, Ing HH et al. Estimated incidence of open-angle glaucoma in Olmsted County, Minnesota. Ophthalmology. 2001; 108: 882-886.
Tenkir A, Solomon B, Deribew A. Glaucoma subtypes in Ethiopian Clinic Patients. J Glaucoma. 2013; 22 (2): 110-116.
Vajaranant TS, Pasquale LR. Estrogen deficiency accerates aging of the optic nerve. Menopause 2012; 19 (8): 942-947.
Voleti VB, Hubschman JP. Age-related eye disease. Maturitas. 2013; 75 (1): 29-33.
McMenamin PG, Lee WR, Aitken DA. Age related changes in the human outflow apparatus. Opthalmology. 1986; 93: 194-209.
Miyazaki M, Segawa K, Urakawa Y. Age related changes in the trabecular meshwork of of the normal human eye. Jap J Opthalmol. 1987; 31: 558-569.
López-López G, Gastélum-Guerrero J. Prevalencia de glaucoma primario en la coordinación universitaria del Hospital Civil de Culiacán en el periodo 2003-2005. Bol Med UAS. 2006; 12 (2): 12-15.
Velasco-Gallegos G, Noriega-Ramírez ME. Prevalencia del glaucoma en población definida en Monterrey, Nuevo León, México. Rev Mex Oftalmol. 2002; 76 (1): 24-29.
Gilbert-Lucido ME, García-Huerta M, Ruiz-Quintero N et al. Estudio epidemiológico de glaucoma en población mexicana. Rev Mex Oftalmol. 2010; 84 (2): 86-90.
Broman AT, Muñoz B, Rodriguez J et al. The impact of visual impairment and eye disease on visio-related quality of life in a Mexican-American population: Proyecto VER. Invest Ophthalmol Vis Sci. 2002; 43: 3393-3398.
Varma R, Wang D, Wu C et al. Four-Year incidence of open-angle glaucoma and ocular hypertension: The Los Angeles Latinos Eye Study. Am J Ophthalmol. 2012; 154: 315-325.