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ISSN 1561-3011 (Electronic)

2013, Number 4

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Rev Cubana Invest Bioméd 2013; 32 (4)

Antioxidant capacity of whole-body methanolic extracts of the beetle Ulomoides dermestoides (Chevrolat, 1893)

Mendoza MD, Salgado YM, Durant IL

Language: Spanish
References: 13
Page: 402-410
PDF size: 198.32 Kb.


ABSTRACT

Introduction: Ulomoides dermestoides is a beetle used in traditional Oriental medicine. In Central and South America beetles are eaten alive as a treatment for asthma and rheumatoid arthritis, but few scientific studies validate this therapy.
Objective: Evaluate the antioxidant capacity of whole-body methanolic extracts of U. dermestoides.
Methods: Extracts were obtained by discontinuous extraction with 48 % and 96 % MeOH. Antioxidant capacity was determined by the ORAC method and the 2.2-diphenyl-1-picrylhydrazyl (DPPH) radical reduction assay.
Results: All extracts showed antioxidant capacity, but the extract obtained with 48 % MeOH and 48 h extraction time (UD4848) exhibited higher activity: ORAC= 3.65±0.5 trolox equivalents, reduction DPPH30min= 81.7 % and IC50 of DPPH30min= 23 µg/mL. The main components in extract UD4848 were saturated and unsaturated fatty acids, n-pentadecanol and 4-ethyl resorcinol.
Conclusions: The antioxidant activity of methanolic extracts of U. dermestoides may explain its use in folk medicine.


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