2000, Number 4
<< Back Next >>
Rev Inst Nal Enf Resp Mex 2000; 13 (4)
Solitary pulmonary node. Clinicopathological study of 122 cases.
Villalba CJ, Margarita Salazar FM, Pérez NJ, Morales GJ
Language: Spanish
References: 17
Page: 211-214
PDF size: 155.32 Kb.
ABSTRACT
Objective: To determine the frequency and clinicopathological characteristics of solitary pulmonary nodule at the Instituto Nacional de Enfermedades Respiratorias.
Material and methods: Patient files from the Surgical Pathology Department of the Instituto Nacional de Enfermedades Respiratorias were selected from January 1, 1984, to December 31, 1999 with pathological anatomy or clinical diagnosis of solitary pulmonary nodule.
Results: A total of 122 cases of solitary pulmonary nodule were found, 50% males and 50% females. Age varied from 3 to 81 years (average 54.5). Twenty-three (1.9%) were younger than 35 years of age. Smoking was positive in 47%. Histological diagnosis was given 82%; the most frequent was granuloma, with 70%, malignant tumors, 13%, benign tumors, 4%, chronic non-specific inflammation, 11% and others, 2%. Of the 13 cases of malignant tumors, 92% corresponded to primary pulmonary tumors, with predominance of adenocarcinoma, 1 metastasic tumor, 4 cases of benign tumors. Of 70 cases of granulomas, 34 were tuberculomas. The size of the solitary pulmonary nodule varied between 0.5 and 3.5cm of largest diameter.
Conclusions: In the present study, granulomas are more frequent, and malignant tumors more infrequent than other series. A comparison of malignancy prevalence with reports by other authors shows that this series is lower, probably due to the higher prevalence of tuberculosis granuloma among our population.
REFERENCES
Gasparini S, Ferretti M, Secchi EB, Baldelli S, Zucatosta L, Gusella P. Integration of transbronchial and percutaneous approach in the diagnosis of peripheral pulmonary nodules or masses. Experience with 1,027 consecutive cases. Chest 1995; 108: 131-137.
Cummings SR, Lillington GA, Richard RJ. Managing solitary pulmonary nodules. The choice of strategy is a “Close call”. Am Rev Respir Dis 1986; 134: 453-460.
Lillington GA, Caskey CI. Evaluation and management of solitary and multiple pulmonary nodules. Clin Chest Med 1993; 14: 111-119.
Swensen SJ, Jett JR, Payne WS, Viggiano RW, Pairolero PC, Trastek VF. An integrated approach to evaluation of the solitary pulmonary nodule. Mayo Clin Proc 1990; 65: 173-186.
Lillington GA. Pulmonary nodules: Solitary and múltiple. Clin Chest Med 1982; 3: 361-367.
Goldberg SK, Walkenstein MD, Steinbach A, Aranson R. The role of staging bronchoscopy in the assessment of a solitary pulmonary nodule. Chest 1993; 104: 94-97.
Bernard A, The Thorax Group. Resection of pulmonary nodules using Video-Assisted thorac surgery. Ann Thorac Surg 1996; 61: 202-205.
Rico-MFG, Villanueva-SCM, Sánchez-JA, Espinosa-PJL, Espinosa-LF, Garbay-CHH. ¿Es el nódulo pulmonar motivo de controversia? Rev Inst Nal Enf Resp Mex 1989; 2: 78-81.
Ibarra-Pérez C, Kelly-García J, Fuentes-Mattos RD. Nódulo pulmonar solitario en el Departamento de Cirugía de Tórax de un hospital oncológico. Rev Inst Nal Enf Resp Mex 1997; 3: 164-167.
Criales CJL, Saldaña Y, Velarde F, Cardoso RM. Nódulos pulmonares. Evaluación del reforzamiento utilizando la tomografía computada helicoidal. Rev Inst Nal Enf Resp Mex 1997; 10: 32-37.
Milman NF, Faurschou P, Grode G. Diagnostic yield of transthoracic needle aspiration biopsy following negative fiber of bronchoscopy in 103 patients with peripheral circumscribed pulmonary lesions. Respiration 1995; 62: 1-3.
Weber W, Young C, Abdel-Dayem HM. Assessment of pulmonary lesions with 18F-fluorodeoxyglucose positron imaging using coincidence mode gamma cameras. J Nucl Med 1999; 40: 574-578.
Lowe VJ, Fletcher JW, Gober L. Prospective investigation of positron emission tomography in lung nodules. J Clin Oncol 1998; 16: 1075-1084.
Prauer HW, Weber WA, Romer W. Controlled prospective study of positron emission tomography using the glucose analogue 18F-fluorodeoxyglucose in the evaluation of pulmonary nodules. Br J Surg 1998; 85: 1506-1511.
Mastin ST, Drane WE, Harman EM. FDG SPECT in patients with lung masses. Chest 1999; 115: 1012-1017.
Blum JE, Handmaker H, Rinne NA. The utility of somatostatin-type receptor binding peptide radiopharmaceutical (P829) in the evaluation of solitary pulmonary nodules. Chest 1999; 115: 224-232.
Swensen SJ, Viggiano RW, Midthun DE. Lung nodule enhancement at CT: multicenter study. Radiology 2000; 214: 73-80.