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2015, Number 1

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VacciMonitor 2015; 24 (1)

Preclinical biomodels for Vibrio cholerae vaccines

Oliva-Hernández R

Language: Spanish
References: 12
Page: 4-9
PDF size: 55.65 Kb.


Text Extraction

I would like to deepen on some of the topics discussed regarding the articles published in the journal Vaccimonitor in the Volume 17 Number 1 of 2008, and the volume 23 number 3 of 2014. They describe the application, use and development of different biomodels for researches, aimed at obtaining vaccine candidates against human cholera, which could contribute to a better understanding of the biomodels used and properly evaluate its scope and limitations.


REFERENCES

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  2. Fu Y, Mekalanos JJ. Infant Rabbit Colonization Competition Assays. Bio–Protocol 2014;4(11):e1147. Disponible en: http://www.bio-protocol.org/e1147

  3. Oliva R, García H, Infante JF, García L, Pérez JL, Cedré B, et al. Biomodelo para la evaluación de cepas atenuadas como candidatos vacunales contra el cólera humano. I. Estudio de la virulencia, capacidad de colonización y adherencia a la mucosa intestinal. VacciMonitor 2008;17(1):1-6.

  4. Alam A, Laroque RC, Harris JB, Vanderspurt C, Ryan ET, Qadri F, et al. Hyperinfectivity of human-passage Vibrio cholerae can be modeled by growth in the infant mouse. Infect Immun. 2005;73(10):6674-9.

  5. Ledón T, Ferrán B, Vichi J, Suzarte E, Oliva R, Fando R. Evaluación en modelos animales de cepas vivas atenuadas de Vibrio cholerae O139. Revista CENIC Ciencias Biológicas 2010;41(Edición Especial 1):1-12.

  6. Sawasvirojwong S, Srimanote P, Chatsudthipong V, Muanprasat C. An Adult Mouse Model of Vibrio choleraeinduced Diarrhea for Studying Pathogenesis and Potential Therapy of Cholera. PLoS Negl Trop Dis 2013;7(6):e2293. doi:10.1371/journal.pntd.0002293.

  7. García L, Benitez J. Hacia el desarrollo de una vacuna eficaz contra el cólera. VacciMonitor 1996;5(2):2-6.

  8. Kondo M, Yamato M, Takagi R, Murakami D, Namiki H, Okano T. Significantly different proliferative potential of oral mucosal epithelial cells between six animal species. J Biomed Mater Res 2014;102(6):1829-37.

  9. Oliva R, García HM, Infante JF, Pérez JL, Cedré B, Valmaseda T, et al. Biomodelos para la evaluación de cepas atenuadas como candidatos vacunales contra el cólera humano. Estudio de la toxigenicidad, inmunogenicidad y protección. VacciMonitor 2014;23(3):100-9.

  10. Spira WM, Sack RB, Froehlich JL. Simple adult rabbit model for Vibrio cholerae and enterotoxigenic Escherichia coli diarrhea. Infect Immun 1981;32:739-47.

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  12. Kang SS, Yang JS, Kim KW, Yun CH, Holmgren J, Czerkinsky C, et al. Anti-bacterial and anti-toxic immunity induced by a killed whole-cell-cholera toxin B subunit cholera vaccine is essential for protection against lethal bacterial infection in mouse pulmonary cholera model. Mucosal Immunology 2013;6(4):826-37.




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