2012, Number 4
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Ann Hepatol 2012; 11 (4)
Acute autoimmune hepatitis presenting with peripheral blood eosinophilia
Chowdry S, Rubin E, Sass DA
Language: English
References: 22
Page: 559-563
PDF size: 151.55 Kb.
ABSTRACT
Peripheral blood eosinophilia has been described in a broad variety of allergic, infectious, neoplastic and
autoimmune diseases. To the best of our knowledge blood eosinophilia has never previously been reported
in association with isolated autoimmune hepatitis (AIH) in the absence of other autoimmune conditions. Herein
we report an interesting case of an 18 year old man who presented to our hospital with an acute autoimmune
hepatitis diagnosed on the basis of clinical features, serology and histopathology. He was noted to
have a moderate peripheral eosinophilia at diagnosis which resolved within days of initiation of corticosteroids
for treatment of the AIH. Given the absence of other systemic conditions or drugs which may have
produced the eosinophilia and its rapid resolution with treatment of the underlying liver disease, we wished
to highlight this rather novel presentation of AIH.
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