2012, Number 4
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Ann Hepatol 2012; 11 (4)
Outcomes of choledochal cysts with or without intrahepatic involvement in children after extrahepatic cyst excision and Roux-en-Y hepaticojejunostomy
Congo K, Lopes MF, Oliveira PH, Matos H, Basso S, Reis A
Language: English
References: 21
Page: 536-543
PDF size: 102.03 Kb.
ABSTRACT
Background. Type I and type IV-A choledochal cysts (CC) in Todani’s classification are the most frequent
types of CC. Unlike type I cyst, in which the dilatation is confined to the extrahepatic bile duct, type IV-A
affects both extra and intrahepatic ducts. Aim. To review our experience of complete cyst excision with
Roux-en-Y hepaticojejunostomy for the treatment of type I and type IV-A CC in childhood, in order to better
characterize these entities.
Material and methods. Data was collected retrospectively from a cohort
of children who underwent cyst resection for CC from 1989 to 2011 in our institution.
Results. Twelve patients
were submitted to surgical excision of extrahepatic cyst and hepaticojejunostomy for treatment of
type I (n = 6) and type IV-A (n = 6) cysts, with a complication rate of 25% (n = 3) and no mortality. Long
term follow-up was available in 92% of patients, with a median of 10 years (2-22 years). Morbidities consisted
of bile leak (2 patients) and late-onset cholestasis (1 patient); two of these required anastomotic revision.
The results did not reveal any significant differences between the groups regarding postoperative
outcomes (P › 0.05). Preoperative intrahepatic dilatation was found to permanently vanish in 83% of patients
diagnosed with type IV-A cyst after operative repair.
Conclusions. Intrahepatic dilatation of type IV-A
cyst in children did not adversely affect the postoperative outcome after conventional surgical repair.
This operative approach was effective in the management of type I and type IV-A cysts.
REFERENCES
Hung MH, Lin LH, Chen DF, Huang CS. Choledochal cysts in infants and children: experiences over a 20-year period at a single institution. Eur J Pediatr 2011; 170: 1179-85.
Visser BC, Suh I, Way LW, Kang S-M. Congenital choledochal Cysts in Adults. Arch Surg 2004; 139: 855-60.
Todani T, Watanabe Y, Narusue M, Tabuchi K, Okajima K. Congenital bile duct cysts: Classification, operative procedures, and review of thirty-seven cases including cancer arising from choledochal cyst. Am J Surg 1977; 134: 263-9.
Todani T, Narusue M, Watanabe Y, Tabuchi K, Okajima K. Management of congenital choledochal cyst with intrahepatic involvement. Ann Surg 1978; 187: 272-80.
Stringer MD, Dhawan A, Davenport M, Mieli-Vergani G, Mowat AP, Howard ER. Choledochal cysts: lessons from a 20 year experience. Arch Dis Child 1995; 73: 528-31.
Ohi R, Koike N, Matsumoto Y, Ohkohchi N, Kasai M. Changes of intrahepatic bile duct dilatation after surgery for congenital dilatation of the bile duct. J Pediatr Surg 1985; 20: 138-42.
Chapman RW. Risk factors for biliary tract carcinogenesis. Ann Oncol 1999; 10(Suppl. 4): 308-11.
Ono S, Fumino S, Shimadera S, Iwai N.Long-term outcomes after hepaticojejunostomy for choledochal cyst: a 10- to 27-year follow-up. J Pediatr Surg 2010; 45: 376-8.
Shimamura K, Kurosaki I, Sato D, Takano K, Yokoyama N, Sato Y, Hatakeyama K, et al. Intrahepatic cholangiocarcinoma arising 34 years after excision of a type IV-A congenital choledochal cyst: report of a case. Surg Today 2009; 39: 247-51.
Bernardes A, Lopes MF, Reis A, Coimbra M. Choledochal cyst. Report of 3 cases. Rev Port Pediatr 1991; 22: 403-7.
Nguyen Thanh L, Hien PD, Dung le A, Son TN. Laparoscopic repair for choledochal cyst: lessons learned from 190 cases. J Pediatr Surg 2010; 45: 540-4.
Miyano T, Yamataka A, Kato Y, Segawa O, Lane G, Takamizawa S, Kohno S, et al. Hepaticoenterostomy after excision of choledochal cyst in children: a 30-year experience with 180 cases. J Pediatr Surg 1996; 31: 1417-21.
Visser BC, Suh I, Way LW, Kang SM. Congenital choledochal cysts in adults. Arch Surg 2004; 139: 855-60.
Calvo-Ponce JA, Reyes-Richa RV, Rodríguez Zentner HA. Cyst of the common hepatic duct: treatment and proposal for a modification of Todani’s classification. Ann Hepatol 2008; 7: 80-2.
She WH, Chung HY, Lan LC, Wong KK, Saing H, Tam PK. Management of choledochal cyst: 30 years of experience and results in a single center. J Pediatr Surg 2009; 44: 2307-11.
Stain SC, Guthrie CR, Yellin AE, Donovan AJ. Choledochal cyst in the adult. Ann Surg 1995; 222: 128-33.
Hill R, Parsons C, Farrant P, Sellars M, Davenport M. Intrahepatic duct dilatation in type 4 choledochal malformation: pressure-related, postoperative resolution. J Pediatr Surg 2011; 46: 299-303.
Koshinaga T, Inoue M, Ohashi K, Sugito K, Ikeda T, Hagiwara N, Tomita R. Persistent biliary dilatation and stenosis in postoperative congenital choledochal cyst. J Hepatobiliary Pancreat Sci 2011; 18: 47-52.
Dabbas N, Davenport M. Congenital choledochal malformation: not just a problem for children. Ann R Coll Surg Engl 2009; 91: 100-5.
Urushihara N, Fukuzawa H, Fukumoto K, Sugiyama A, Nagae H, Watanabe K, Mitsunaga M, et al. Totally laparoscopic management of choledochal cyst: Roux-en-Y Jejunojejunostomy and wide hepaticojejunostomy with hilar ductoplasty. J Laparoendosc Adv Surg Tech A 2011; 21: 361-6.
Yamaguchi M. Congenital choledochal cyst. Analysis of 1,433 patients in the Japanese literature. Am J Surg 1980; 140: 653-7.