2015, Number 2
Rev Mex Angiol 2015; 43 (2)
Disfunción endotelial y debut trombótico arterial en enfermedades reumatológicas. A propósito de dos casos
Santillán-Aguayo E, Córdova-Quintal P, Carbajal-Robles V, Lecuona-Huet NE, Campero-Urcullo A
Language: Spanish
References: 10
Page: 81-84
PDF size: 335.45 Kb.
ABSTRACT
Introduction. Chronic inflammatory autoimmune diseases are a heterogeneous group in which endothelial dysfunction has as its ultimate expression increased cardiovascular risk due to accelerated atherosclerosis.Objective. Describe two cases of chronic inflammatory autoimmune diseases with arterial complications as disease onset.
Case report. We present two cases of patients with secondary arterial thrombotic debut with endothelial dysfunction inherit to polyarteritis nodosa and antiphospholipid syndrome confirmed by biopsy.
Conclusions. Endothelial dysfunction, cardiovascular risk factors and complications arising from the physiological and hemodynamic implications have been extensively studied, however, focused on coronary artery disease; so, establishing an association to peripheral artery disease will broaden the panorama of study and treatment in this type of patients to reduce long term complications caused by late detection.
REFERENCES
Soltész P, Dér H, Kerekes G, Szodoray P, Szücs G, Dankó K, Shoenfeld Y, et al. A comparative study of arterial stiffness, flow-mediated vasodilation of the brachial artery, and the thickness of the carotid artery intima-media in patients with systemic autoimmune diseases. Clin Rheumatol 2009; 28(6): 655-62.