2014, Number 3
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Revista Cubana de Cirugía 2014; 53 (3)
Primary Non Hodgkin´s lymphoma of the adrenal gland
Burneo EM, Pérez DMD, Bernardos GL, Osorio PS, Cuadrado AM, Turégano FF
Language: Spanish
References: 10
Page: 318-323
PDF size: 115.64 Kb.
ABSTRACT
Primary non- Hodgkin's lymphoma of the adrenal gland is very rare. Its initial
diagnosis is difficult and needs to be histological. Diffuse large B- cell lymphoma is the
most common histological type. This is the report of a 62 years old woman, who was
performed abdominal tomography to disclose a 18 cm tumor in the adrenal gland with
carcinoma characteristics. The tumor was removed and the final pathologic diagnosis
was diffuse large B-cell lymphoma. This type of lymphoma has poor prognosis since
the average survival rates are roughly 13 months. There is no well-defined therapeutic
regimen, although the most widely accepted treatment is R-CHOP scheme. The roles of
radiotherapy and tumor resection are not clearly established. Primary adrenal
lymphoma should be considered in the differential diagnosis of patients presenting with
an adrenal mass. When this condition is suspected, then it is advisable to perform a
imaging-guided needle biopsy to avoid unnecessary surgery.
REFERENCES
Armin R, Stephen IF. Primary adrenal lymphoma: A systematic review. Ann Hematol. 2013;92(12):1583-93.
Ezer A, Parlakgumus A, Kocer NE, Colakoglu T, Nursal GL, et al. Primary adrenal non-Hodgkin´s lymphoma: Report of two cases. Turk J Gastroenterol. 2011;22(6):643-7.
Ri Kim Y, Seok Kim J, Hong Min J, Hyun Yoon D, Shin HJ, et al. Prognostic factors in primary diffuse large B-cell lymphoma of adrenal gland treated with rituximab-CHOP chemotherapy from the Consortium for Improving Survival of Lymphoma (CISL). J Hematology Oncol. 2012;5:49-57.
Wang JP, Sun HR, Li YJ, Bai RJ, Gao S. Imaging features of primary adrenal lymphomma. Chin Med J. 2009;122(20):2516-20.
Mozos A, Ye H, Chuang WY, Chu JS, Huang WT, et al. Most primary adrenal lymphomas are diffuse large B-cell lymphomas with non-germinal center B-cell phenotype, BCL6 gen rearrangement and poor prognosis. Modern Pathol. 2009;22:1210-7.
Aggarwal A, Kotru M, Sharma V. Adrenal insufficiency in primary adrenal lymphoma: Innocuous presentation of a rare sinister illness. Niger J Clin Pract. 2011;14:115-7.
Bouchikhi AA, Tazi MF, Amiroune D, Mellas S, El Ammari J, et al. Primary Bilateral non-Hodgkin´s Lymphoma of the Adrenal Gland: A case report. Case Rep Urol. 2012;3:256-75.
Holm J, Breum L, Stendfeldt K, Friberg Hitz, M. Case Rep Endocrinology. 2012;6382-98.
Rosenberg SA, Diamond HD, Jaslowitz B, Craver LF. Lymphosarcoma: a review of 1269 cases. Medicine. 1961;40:31-84.
Grigg AP, Connors JM. Primary adrenal lymphoma. Clin Lymphoma. 2003;4(3):154-60.