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Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2015, Number 2

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Alerg Asma Inmunol Pediatr 2015; 24 (2)

Descriptive analysis of allergen sensitization in a pediatric population

Soto AS, Partida GA, Romero PMS, Martínez VA, Díaz GL, Bautista GSG

Language: Spanish
References: 35
Page: 40-53
PDF size: 270.22 Kb.


ABSTRACT

Introduction: For the start of an allergic disease, an allergen sensitization is indispensable. Allergens vary between different geographic regions and its proper identification allows for effective treatment measures. Objective: Identify to which allergens are sensitized in children aged 1-18 years with symptoms of allergy. Describe to which allergens are sensitized children 1-18 years, by age group and diagnosis. Describe the pattern of sensitization according to the patient’s age at different ages, describe the concentration of total serum IgE, with the number of sensitization. Methodology: A cross-sectional, observational, descriptive and retrolective design. All clinical records of patients with skin tests during the period August 2011 to December 2013, were reviewed. Results: Allergic diseases reported in order of frequency were: allergic rhinitis 671 patients (60%), 293 asthma patients (26%), other allergic diseases such as atopic dermatitis, urticaria and allergic conjunctivitis was reported in 46 (4%), 27 (2.5%) and 27 patients (2.5%) respectively. Globally, the most frequent sensitizations in the Federal District and State of Mexico were: mites 680 (60%), Dermatophagoides pteronyssinus 317 (28%), Dermatophagoides farinae 269 (24%), Blomia tropicalis 94 (8.4%), trees 667 (54%), Cupressus arizonica 115 (10%), Olea europaea 108 (9.6%), grasses with 241 (19.7%), Cynodon dactylon 51 (4.5%), Phleum pratense 38 (3.2%), Dactylis glomerata 29 (2.6%), weed 217 (17.7%), Chenopodium album 69 (6.1%), Salsola kali 22 (2.9%), Rumex spp 25 (2.2%). The number of sensitizations in function of the concentrations of serum IgE, resulted significant (β = 0.192, p = 0.008), which corresponds to a positive correlation between these two variables.


REFERENCES

  1. Arshad SH, Tariq SM, Matthews S, Hakim E. Sensitization to common allergens and its association with allergic disorders at age 4 years: a whole population birth cohort study. Pediatrics. 2001; 108 (2): E33.

  2. Sánchez-Caraballo J, Diez-Zuluaga S, Cardona-Villa R. Sensibilización a aeroalergenos en pacientes alérgicos en Medellín Colombia. Revista Alergia México. 2012; 59 (3): 139-147.

  3. Wilson NW, Robinson NP, Hogan MB. Cockroach and other inhalant allergies in infantile asthma. Ann Allergy Asthma Immunol. 1999; 83 (1): 27-30.

  4. Pawankar R, Walter Canonica G, Holgate S, Lockey R. Libro Blanco sobre Alergia de la WAO. Resumen Ejecutivo. World Allergy Organization, 2011.

  5. Eder W, Ege MJ, von Mutius E. The asthma epidemic. N Engl J Med. 2006; 355 (21): 2226-2235.

  6. Bousquet J, Bieber T, Fokkens W, Kowalski ML, Humbert M, Niggemann B et al. Rhinitis and asthma represent hot topics for allergy. Allergy. 2009; 64 (1): 1-4.

  7. Heinrich J. Influence of indoor factors in dwellings on the development of childhood asthma. Int J Hyg Environ Health. 2011; 214 (1): 1-25.

  8. Diamant Z, Boot JD, Mantzouranis E, Flohr R, Sterk PJ, Gerth R et al. Biomarkers in asthma and allergic rhinitis. Pulm Pharmacol Ther. 2010; 23 (6): 468-481.

  9. Perzanowski MS, Rönmark E, Platts-Mills TA, Lundbäck B. Effect of cat and dog ownership on sensitization and development of asthma among preteenage children. Am J Respir Crit Care Med. 2002; 166 (5): 696-702.

  10. Torrent M, Sunyer J, Garcia R, Harris J, Iturriaga M, Puig C et al. Early-life allergen exposure and atopy, asthma, and wheeze up to 6 years of age. Am J Respir Crit Care Med. 2007; 176 (5): 446-453.

  11. Torrent M, Sunyer J, Muñoz L, Cullinan P, Iturriaga MV, Figueroa C et al. Early- life domestic aeroallergen exposure and IgE sensitization at age 4 years. J Allergy Clin Immunol. 2006; 118 (3): 742-748.

  12. Crisafulli D, Almqvist C, Marks G, Tovey E. Seasonal trends in house dust mite allergen in children’s beds over a 7-year period. Allergy. 2007; 62 (12): 1394-1400.

  13. LeMasters GK, Wilson K, Levin L. High prevalence of aeroallergen sensitization among infants of atopic parents. J Pediatr. 2006; 149 (4): 505-511.

  14. Nolte H, Kowal K, DuBuske L. Overview of skin testing for allergic disease. UpToDate. 2013.

  15. Larenas-Linnemann D, Ortega-Martell J, Río-Navarro B, Rodríguez-Pérez N, Arias-Cruz A, et al. Guía Mexicana de Práctica Clínica de Inmunoterapia. Rev Alergia Mex. 2011; 58 (1): 3-51.

  16. Orozco MS, Chong QLE, Penagos PM, Huerta LJG, Sandino RC et al. Utilidad de las pruebas cutáneas por punción (prick test) con extracto de guante, extracto crudo de látex y proteínas purificadas (pseudoheveína, heveína, forma molecular de la heveína y heveína modificada químicamente) en el diagnóstico de alergia al látex. Alerg Asma Inmunol Pediatr. 2006; 15 (1): 6-29.

  17. Sheehan WJ, Rangsithienchai PA. Age-specific prevalence of outdoor and indoor aeroallergen sensitization in Boston. Clinic Pediatr (Phila). 2010; 49 (6): 579-585.

  18. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. NHLBI/WHO Workshop Report. National Heart, Lung and Blood Institute. National Institutes of Health, Bethesda; 2002.

  19. Larenas-Linnemann et al. Allergen sensitization linked to climate and age, not to intermittent-persistent rhinitis in a cross-sectional cohort study in the (sub) tropics. Clin Transl Allergy. 2014; 4: 20.

  20. Programa Estratégico Forestal del Distrito Federal (PEF-DF) 2006-2025.

  21. Heinzerling L, Frew AJ, Bindslev-Jensen C et al. Standard skin prick testing and sensitization to inhalant allergens across Europe-a survey from the GALEN network. Allergy. 2005; 60 (10): 1287-1300.

  22. Cardona R, Orrego J, Montoya F et al. Sensibilidad cutánea Medellin, Colombia/Skin sensitization to aeroallergens in patient with asthma of Medellin, Colombia. Revista de la Asociación Colombiana de Alergia e Inmunología. 2003; 11 (1): 7.

  23. Sánchez J, Diez S, Cardona R. Sensibilización a aeroalérgenos en pacientes alérgicos de Medellín, Colombia. Revista Alergia México. 2012; 59 (3): 139-147.

  24. Cavazos GM, Guerrero NB, Ramírez AD. Comparative mites and cockroaches sensitization study in three cities of Mexico. Rev Alerg Mex. 2008; 55: 234-239.

  25. Gaspar-López A, López-Rocha E, Rodríguez-Mireles K, Segura-Méndez N, Del Rivero-Hernández L. Prevalencia de polinosis en pacientes con asma, rinitis y conjuntivitis alérgicas en la zona sur del Distrito Federal, 2007-2013. Revista Alergia México. 2014; 61: 147-152.

  26. Boletín de la UNAM DGCS-418 Ciudad Universitaria.

  27. Red Mexicana de Aerobiología (Rema) de la UNAM.

  28. Terán JLM, Haselbarth-López MMM, Quiroz-García DL. Alergia, pólenes y medio ambiente. Gac Méd Méx. 2009; 145 (3): 215-222.

  29. Johansson SG, Bieber T. Revised nomenclature for allergy for global use: Report of Nomenclature Review Committee of the World Allergy Organization. October 2003. J Allergy Clinic Immunol. 2004; 113 (5): 832-836.

  30. Stern DA, Lohman IC. Dynamic changes in sensitization to specific aeroallergens in children raisen in a desert enviroment. Clin Exp Allergy. 2004; 39 (10): 1563-1669.

  31. Alp H, Yu BH, Grant EN, Rao V, Moy JN. Cockroach allergy appears early in life in inner-city children with recurrent wheezing. Ann Allergy Asthma Immunol. 2001; 86: 51-54.

  32. Wahn U, Lau S, Bergmann R, Kulig M, Forster J, Bergmann K et al. Indoor allergen exposure is a risk factor for sensitization during the first three years of life. J Allergy Clin Immunol. 1997; 99 (6 Pt 1): 763-769.

  33. Wickens K, Pearce N, Siebers R, Ellis I, Patchett K, Sawyer G et al. Indoor environment, atopy and the risk of the asthma in children in New Zealand. Pediatr Allergy Immunol. 1999; 10: 199-208.

  34. Sporik R, Holgate ST, Platts-Mills TA, Cogswell JJ. Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood. A prospective study. N Engl J Med. 1990; 323: 502-507.

  35. Tatto-Cano MA, Sanín-Aguirre LH, González V, Ruiz-Velasco Silvia, Romieu. Prevalencia de asma, rinitis y eczema en escolares de la ciudad de Cuernavaca, México. Salud Pública Méx. 1997; 39 (6): 497-506.




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