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Órgano oficial de la Facultad de Odontología, UNAM

2015, Number 3

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Rev Odont Mex 2015; 19 (3)

Non surgical periodontal treatment in patients with gingivitis and moderate periodontitis. Biochemical and microbiological response

Macín-Cabrera S, Sanz-Alonso M, Castrillón-Rivera L, Palma-Ramos A, Noguez-Méndez N, Quirino-Barreda C, Rubio-Martínez A

Language: Spanish
References: 47
Page: 155-164
PDF size: 266.69 Kb.


ABSTRACT

Objective: To ascertain inflammatory response through interleukin 1β presence and identify pathogenic microorganisms as possible immunological and microbiological markers in diagnosis and treatment non-surgical periodontal in patients with gingivitis and moderate chronic periodontitis in a sample of Mexican population. Material and methods: In the present prospective cohort study, 18 patients with signs of gingivitis and 17 patients with moderate chronic periodontitis were selected. Samples of subgingival biofilm and of crevicular gingival fluid were collected. Interleukin 1β was quantified during the pre-treatment, post-treatment and maintenance phases of the non- surgical periodontal treatment. Continuous variables were analyzed with the Student test, as well as categorical variables which were analyzed with the Turkey-Kramer test. For independent groups the Pearson test was used. Results: Microbiological response variables showed that porphyromonas gingivalis Prevotella intermedia, Fusobacterium nucleatum, Aggregatibacter actinomycetemcomitans significantly decreased in subjects with gingivitis, Porphyromonas gingivalis, Tannerella forsythia, Fusobacterium nucleatum, Aggregatibacter actinomycetemcomitans and Actinomyces ssp. decreased in cases. Biochemical response variables showed significant decrease in IL-1β concentration and total count in individuals with moderate chronic periodontitis in treatment maintenance phase. The same result applied to clinical response variables. Conclusions: There is a decrease in Interleukine 1β levels with decrease in microflora. Interleukin 1β are sensitive markers for diagnosis of periodontal disease and assessment of its severity.


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