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Colegio de Medicos y Cirujanos República de Costa Rica

2015, Number 614

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Rev Med Cos Cen 2015; 72 (614)

Diabetes mellitus y atrofia óptica: la clave del diagnóstico del sindrome de Wolfram

Gil-Collado M

Language: Spanish
References: 27
Page: 167-173
PDF size: 74.87 Kb.


ABSTRACT

Wolfram syndrome od DIMOAD is a rare neurodegenerative and multisystemic disease with: Diabetes insipidus, diabetes mellitus, optic atrophy and deafness caused by a mutation in the protein wolframin. Early diagnosis and prevention of complications are the two branches of its treatment, because even though an important progression in the treatment has been done, with substances such as 4-phenylbutyric acid, there is still no curative treatment.


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